Hypoglycemic activity of Haloxylon salicornicum and Glibenclamide were studied in normal and diabetic rabbits. The drugs were adminstered once daily at dose of lg / Kg at H.salicorm'cum and 10 mg / Kg at Glibenclamide by gavage for one month. Serum glucose level, creatinine level, total bilirubine and total protein were reduced significantly in 15-30 days. The serum Transaminase (AST and ALT activities) had effect on the treated groups.

This study was conducted to investigate the effect of chitosan sheets onA inflammation. Accordingly chitosan sheet was isolated and prepared from theexoskeleton of the native shrimps in Basrah Province. The inflammation was induced andevaluated by polyvinyl sponge to determine the events which occur during theinflammatory process during different intervals in the presence or absence of chitosan‘ sheets .For this purpose 24 male rabbits were used and two linear skin incisions (2 cm)were made on the dorsal aspect in both sides of each rabbit. The inflammatory process atl,3,7&l5 day post wounding was evaluated macroscopically in terms of hyperemia,suppuration, dryness, and adhesion of margins and microscopically in terms of infiltrationof inflammatory cells specially neutrophils and macrophages, fibrovascular granulationtissue. _. The ‘results of macroscopic evaluation revealed that '-It first post wounding day thetest wound was significantly (p<0.05) more hyperemic than control wounds followed bya significant decrease in the severity of hyperemia in test wounds at ls‘, 3rd, 7"‘, and 15"‘post wounding days (p<0.05). The test wounds was more dry with less suppuration to_ words the end of the experiment than control wounds (p<0.05). The adhesive contactbetween the margin of the wounds was significantly higher in test wounds than in controlwounds through out the period of experiment (p<0.05).

In an assessment of cellular immunity in Guinea pigs following transfer factor and sensitized spleen cell transfer using the erythrocytes: lyphocytes rosette test (E-rosette test). . The results revealed the following: p _ There is increase in the mean number of E-rosette forming active and total T lymphocytes in the sensitized transfer factor and sensitized spleen cell recipient groups comparable to control groups received normal spleen cell extract and normal spleen cells. These findings indicate that E-rosette "forming cells are of cellular immunological sinificance. .

Biopsy were taken from 50 patients in order to cultivate Helicobacter pylori and blood samples to detect anemia , differential white blood eellcount and blood groups . The results showed that anemia was found in 48% of the patients while lymphocyte elevated in 44% of them , blood group 0 had the higher percentage ( 42% ) in those patients among the other blood group types" . ' . _ _ INTRODUCTION - Helicobacter pylori is a gram-negative microorganism that secretes many substances including ammoina , mucolytic enzymes ( adhesins , catalase and urease ) and acid secrete inhibitory proteins.(8) In addition to that it secrets toxin like vacuolating cytotoxin A (vacA).(7). - — Adhesin allows the organism to adhere , catalase might protect the organisum from the immune system , urease increase the secretion of gastrin which stimulate the intestinal‘ tissues to grow faster , and so could result in increased cancer risk .Urease is reponsible for hydrolyzing urea to NH3 and CO2, and acts as also protective by forming an alkalin environment around the organism . The combination of NH3 ,_Co2 and inhibitory proteins allows the bacteria to setup locallized pockets where it can neutralize even the acidity of ' blood type 0 stomachs The genetics of the secretor and non —-secretor system interact to alter an individuals risk for ulcer. In several studies , non—secretors of ABO substances have been found to have significantly higher rate ofduodenal and peplic ulcer .( 8) fl._ pylori infection increases the percentage of peripheral lymphocytes above the upper limit of referential.values .(l0)e ' ‘ Recent evidence suggests that fl_. pylori infection could cause iron deficiency anemia ( IDA ).(2). Adolescent femal athletes may have development of [_{_.__pylori associated ( IDA ) which can be managed by Q pylori eradication (5 ) . H. pylori may have a role in causing IDA in school-age children (3 )

The inhibitory effects of five extracts.‘ ‘(S0 aclueouis lethanollil ':abetone,' ethylacetate, chloerform and water) from F oeniculum Vulgare (L) Mill, on the growth of Gram-positive bacteria (seven isolates) and Gram-negative bacteria (seven isolates) werebyusing the paper disc plate method (1). All the investigated extracts exhibited various degree of inhibition on all tested bacteria, except 50% aqueous ethanal extract ‘which _was unable to inhibit the growth of Bacillus. subtilis A bacteria

The morphology and the Vasculaturc of the ltdncy of the Buffaloes was escr: lei lined BL.lfI‘t-11005 kidneys was eorrc at u. Information obtained from gross dissection o em )1 . Th‘ f wtionrll with latex and Cold cure solution injected vascular and in excI‘et0TY 035” " u‘ ‘ significance of the renal apparatus was discussed

Forty sera of patients infected with Leishmania donovani and (10) sera from apparently healthy subject were tested by single radial immunodiffusion to visualize the concentration of IgG, IgM, IgA, C3 and C4. Recent results showed that there was a highly significant increase in the level of IgG, IgM, C3 and C4 but there were no significant differences in the level of IgA between the two—studied groups.

It can be prepared a good drug or antibiotic depending on this research .its same as build a beautiful house depending on a good building factors, this research is about the important relation between the biological activity (the activity against the microbes) and stereochemical structure of the preparing compounds .To obtain this relation two ‘compounds has been prepared and tested on different species - r j (§_t.aureus, _F:._c_ofi, candida albicans), one of these two compounds has show more activity than the other even the difference between them is simple, this question was push us to study the more active compound (compound (l)), why it more active against the microbes, _ also this question led us to estimate the important relation five factors effecting the relation, th1s relation was obtained not from the two compounds only, but depending on more than these compounds the relation was obtained, also preparing compounds in this research are enough to illustrate the five factors leading to the important relation. _ ‘To understanding the research idea or the important relation, compound (3) was _ prepared which its more active than the two compounds. , ' All the three compounds have identify by melting point, solubility test, CHNSO analyzer, l.R., and uv-visible spectra

plant /I/ac van: is a green succulent .cactus-like plant belonging to the lily family ,The.plant has a history of use in folk medicine for skin and otherdisorders. The objective of the study presented in this report was to screen the extracts of this plant for its wound- - healing properties based on its traditional use for wound healing. ethanolic extracts was prepared for topical applications. The dose used was 150 mg/kg daily for 10 days, using the excision wound model in rabbits. Carboxymethyl cellulose (1%) was used as control in . ‘ topical studies. Animals were randomized divided to treatment or control groups, . Wound areas were measured. At the day Il',skin .tissue was excised for histological studies" . Wound areas reduced significantly in all treatment groups compared to respective controls (P < .001). Histology outcomes were consistent with changes in the treatment groups. No differences were detected within the treatment groups. The study permits the conclusion that Aloe Vera has wound—hea‘ling potential

The effects of dimethylaminoazobenzene dye were studied in rats by exposing skin directly to the dye. Twenty one mature rats Rattus norvegicus were divided into three groups and I represented by (control group Tlgroup treated with ether (vehicle) only, and T2 group treated with dimethylaminoazobenzene. dissolved in ether). The obtained results concluded the carcinogenic effects of dimethylaminoazobenzene depending on marked grossly and histological changes represented by appearance of skin cancer (squamous cell carcinoma and basal cell carcinoma) types in T2 group