خيارات البحث
النتائج 221 - 230 من 283
In vitro effect of T-2 mycotoxin on the immune response of mice
1988
Holt, P.S. | DeLoach, J.R.
The in vitro biologic effects of T-2 mycotoxin on the immune response of mice was undertaken. Twenty nanograms of toxin abrogated the immune response to the T-dependent antigen sheep RBC, whereas a partial response was observed when 2 ng was used. Analysis of cell culture viabilities indicated that cell death occurred with toxin doses that conincided with the diminished immune responses. A similar decreased response was observed against the T-independent antigen, TNP-lipopolysaccharide, indicating toxic effects on both B and T lymphocyte populations. Delay of toxin administration as much as 116 hours of the 120-hour incubation period still resulted in a substantially diminished immune response, indicating the toxin acts on both the afferent and efferent immune systems. Equal effects were observed for mice of the b, d, and k haplotype, indicating no apparent strain variability in sensitivity to T-2 mycotoxin effects. These results indicated that T-2 mycotoxin can modulate the immune response, and that this modulation is attributable to direct toxic effects on the cells of the immune system.
اظهر المزيد [+] اقل [-]Case-control study of risk factors associated with nosocomial Salmonella krefeld infection in dogs
1988
Uhaa, I.J. | Hird, D.W. | Hirsh, D.C. | Jang, S.S.
In a case-control study of risk factors associated with an episode of nosocomial Salmonella krefeld infection in dogs at the veterinary medical teaching hospital, data on 20 case dogs and 75 control dogs were obtained by review of hospital records. Univariate and multivariate statistical analyses were carried out for possible risk factors for infection to obtain odds of Salmonella krefeld isolation, given exposure to each risk factor of interest. Compared with control dogs, case dogs were 11.9 times more likely to have been fed rice, 7 times more likely to have had radiography done, 10.2 times more likely to have been a resident in ward 2, 5.6 times more likely to have been given antimicrobial agents orally, 11.3 times more likely to have been given antimicrobial agents parenterally, and 37.9 times more likely to have been given antimicrobial agents orally and parenterally (P less than 0.05).
اظهر المزيد [+] اقل [-]A new cestode, Raillietina (Raillietina) oligocapsulata n. sp., and R. (R.) demerariensis (Daniels, 1895) from Venezuelan mammals
1988
Sato, H. (Hokkaido Univ., Sapporo (Japan). Faculty of Veterinary Medicine) | Okamoto, M. | Ohbayashi, M. | Basanez, M.G.
Angiostrongylus sandarsae Alicata, 1968 (Nematoda: Metastrongyloidea) from Praomys natalensis in Kenya
1988
Kamiya, M. (Hokkaido Univ., Sapporo (Japan). Faculty of Veterinary Medicine) | Fukumoto, S.
Frenkelia sp. from the red-backed vole, Clethrionomys rufocanus bedfordiae, in Hokkaido, Japan
1988
Fujita, O. (Hokkaido Univ., Sapporo (Japan). Faculty of Veterinary Medicine) | Oku, Y. | Ohbayashi, M.
Histological and immunohistochemical studies on the localization of immunoglobulins in porcine placenta
1988
Yano, K. (Hokkaido Univ., Sapporo (Japan). Faculty of Veterinary Medicine) | Hashimoto, Y. | Kitagawa, H. | Kon, Y. | Kudo, N.
Blood supply and microvasculature of the lymph nodes in pigs
1988
Hoshi, N. (Hokkaido Univ., Sapporo (Japan). Faculty of Veterinary Medicine) | Hashimoto, Y. | Kitagawa, H. | Kon, Y. | Kudo, N.
Pseudoparasitism by thelastomatid nematodes in moles, Mogera spp., in Japan
1988
Yokohata, Y. (Hokkaido Univ., Sapporo (Japan). Faculty of Veterinary Medicine) | Jiang, Y.P. | Abe, H. | Ohbayashi, M.
Redescription and multivariate morphometrics of Moguranema nipponicum Yamaguti, 1941
1988
Yokohata, Y. (Hokkaido Univ., Sapporo (Japan). Faculty of Veterinary Medicine) | Abe, H. | Kamiya, M.
Studies on the isolation and sero-typing of salmonella from the faecal material of buffaloes
1988
Rashid, M. | Haider, S.S. | Ahmad, S.M. | Anjum, A.S. (Veterinary Research Inst., Lahore (Pakistan))