This experiment was conducted to determine the effect of hypobaric hypoxia on PCV (packed cell volume), Hb conc. (hemoglobin concentration), RBC No. (red cell number) and red cell GSH (levels of reduced glutathione) and DPG (diphosphoglycerate) in the rabbit. There was a significant rise in all the parameters measured except DPG which did not change during and/or after the hypobaric hypoxia

This study was undertaken to clarify the histopathological changes of pigs naturally infected with hog cholera. Vascular cuffing of the brain was observed in about 97% of the natural cases and all of the experimental cases. Electron microscopic findings on cuffed blood vessels of the brain were endothelial cellular degeneration and infiltration of pleomorphic lymphoid cells. In the rabbits dosed with tissue suspension of the lymphoid organs and isolated hog cholera virus, high body temperature and vascular cuffing of the brain were more significant in pre-injected cases with indian ink

Biochemical and antimicrobial susceptibility tests were conducted on 40 strains of Pseudomonas aeruginosa which originated from diseased chicken. An extensive study of the biochemical properties revealed that the tested strains can be identified with Pseudomonas aeruginosa. Antibiogram showed that all the strains were susceptible to gentamicin, colistin and amikacin but resistant to nitrofurantion, trimethoprim plus sulfamerthoxasole, ampicillin, methicillin and kanamycin and had varying degrees of resistance to other antimicrobials including carbenicillin, sulfomamides, neomycin, streptomycin, tetracycline and chloramphenicol. Three of the most frequent resistance patterns observed were FM (Nitrofurantoin) SXT (Sulfamethoxasole) AM (Ampicillin) ME (Methicillin) KM (Kanamycin) CM (Chloramphenicol) TC (Tetracycline) SM (Streptomycine) NE (Neomycine) SSS Pattern, FM SXT AM ME KM CM TC SM NE SSS CB (Carbenicillin) Pattern and FM SXT AM ME KM CM TC SM Pattern, and these resistance patterns contained 72.5% of the tested strains

This study was done to clarify the histopathological changes of pigs naturally infected with hog cholera. Microscopic observations of the necrotic lesion and inclusion body in the lymphoid organs were carried out in the natural cases of hog cholera and experimental cases inoculated with ALD (challenge) virus and isolated virus strains. Electron microscopic findings of the intranuclear inclusion bodies in the retincular cell of spleen and lymph node were also observed in the experimental cases. The histological findings of necrosis of lymphoid organs were found to contain 35.0% in the natural and 37.5% in the experimental cases. Intranuclear inclusion bodies were found mainly in the reticular cells of lymhoid organ, the epithelium of bronchiole and alevolus, and the vascular endothelium of brain. These inclusion bodies were seen in 40.0% of the natural cases and in all of the experiment cases. The inclusion body appeared to be composed of activated nucleoli and chromatin granuls (interchromatin and perichromatin) by electron microscopy

A seroepidemiological survey on bovine leucosis virus was conducted. Serological studies were analyzed by age groups and the sizes of herds. The number of reactors increased gradually with the advance in the age of cattle and the herd size. The highest rate of BIV carriers was found in the ages between 6 and 8 years, and in the size of herds with 20 to 50 heads. Two out of 6 specimens (33.3%) from the reactors showed the typical type C virus with the size of 90 to 110 nm around microvilli and in intracytoplasmic vacuoles

A seroepidemiological survey for antibodies to bovine leukemia virus in dairy and Korean native cattle in Kyungbuk area, Korea [R.] was performed using BLV p and gp antigens by the ID test. In the dairy cattle (Holstein), thirty of 106 sera (28.3%) form 14 dairy farms were positive for BLV antibodies and 12 of 14 pastures were contaminated with BLV. In the Korean native cattle, seventeen (2.4%) of 699 sera from the slaughter house in Taegu city were positive for BLV antibodies. Of 47 gp-ID positive cattle, 5(10.6%) had antibodies to p antigen

This study was performed to clarify the clinical signs of macroscopical lesions of pigs naturally infected with hog cholera. There was clinical and macroscopical observation on the natural cases of hog cholera and experimental cases inoculated with ALD virus and isolated virus strains. In the clinical inspection of the natural cases, diarrhea (73.1%), blotching of ear (50.0), conjunctivitis (32.7%) and dyspnea (30.8%) were observed. Dyspnea, constipation and erythema of skin were observed mainly in the experimental cases, however, staggering and conjunctivitis in pigs infected with ALD virus were found and convulsion and hemorrhage of skin of pigs infected with isolated virus were seen, respectively. The gross lesions of natural cases were hemorrhage of lymph node (82.5%), pneumonia (55.0%), gastritis and hemorrhage (52.5%), cardial hemorrhage (40.0%) and renal petechiation (37.5%), while in the experimental cases, hemorrhage of lymph node, pneumonia, gastritis and hemorrhage, enteritis and hemorrhage of large intestine and splenic infarction were seen mainly

The presence of fibrinous thrombi in the blood vessels of multiple organs was observed in chickens which died within approximately 3 days post inoculation. The density of fibrinous thrombi (i.e., the number of thrombi per section) was greatest in the lung, followed by spleen, kidney, liver and heart. The cause of death of the chickens after infection with acute fowl cholera was probably due to an endotoxin (septic) shock accompanied with DIC in multiple organs

A polyvalent live Eschericia coli oral vaccine were prepared by the use of 5 field isolates of enteropathogenic E. Coli, serotypes 08: K87, K83a, b; 0138: K81, K88a, c; 0141: K85a, b, K88a, b: 0149: K91, K88a, c and 0157: K'V17' K88a, c. Some field experiments were conducted to investigate the effectiveness of the polyvalent live E. coli oral vaccine in the prevention of neandatal colibacillosis in piglets suckling orally vaccinated sows. Seventy-nine pregnant sows in and intensive pig farm were vaccinated with oral vaccine 4 weeks prior to farrowing and 19 sows were chosen for control. The piglets suckling vaccinated sows showed a significant protection against neonatal enteric colibacillosis during the 2 weeks observation period from the farrowing but no significant differences in protection between vaccinated and control group were observed with piglets older than 15 days

Pathological studies on 6 milk goats administered with urea were carried out to determine the effects of acute and chronic poisoning on the animal. Clinical signs appeared about 10 minutes after ingestion of the urea and they consisted chiefly in dullness, staggering, uncontrolled urination, dyspnoea, frothy salivation, bloating, muscular tremor, humping of back and tetanic spasms. Macroscopic lesions were failure of blood clot, frothy and bloody contents in the highly congested respiratory tract, pulmonary edema, rumenitis and abomatitis accompanying with petechiation of the upper small intestine. Microscopically, the liver showed vacuolar degeneration, fatty change and areas of necrosis and partial proliferation of the interlobular connective tissues in chronic cases. The renal epithelium displayed vacuolar degeneration, necrosis and hyaline casts in their lumens. In the lungs, there were hyperemia, edema, hemorrhages, and acute catarrhal bronchitis. Neuronal degeneration and necrosis in the central nervous system, cattarhal rumenitis, abomatitis, doudenitis and myocaridal hemorrhage were also demonstrated