In the conditions of the Republic of Belarus the was studied the age-specific dynamics of content of total lipids, triglycerides, total cholesterol, phospholipids, total iron and catalase activity in spleen of broiler chicken during the incubation period (1-46 days). The content of total lipids, total cholesterol, and phospholipids was at maximal level at one day-old age, and gradually lowered by the end of growing period. The amount of total iron in ontogeny increased till the 30 day-old age and a bit lowered by the end of growing period. In broilers with lower live weight the iron content in spleen was lower during the whole growing period. The catalase activity had a wave-like character and depended on prophylactic vaccinations undertaken and the amount of lipids in tissues.

In the conditions of the Republic of Belarus taking into consideration the hygienic aspects there were studied the aetiological factors in dermatosis development in productive cows. As a result of realized research it was established that aetiology of skin diseases in the area of a mammary gland were traumas, and following affects were more often marked: skin rhagades of mammillars; wound in the area of a mammary gland and mammillars; fistulas of milk tank vessels; and also sporadic damages of sphincter muscle of teat canal caused by machine milking. This in its turn gives made it possible to consider, that traumas of various character were a contributing factor for occurrence of udder garget - mastitis. In course of the realized analysis there was proved a high therapeutic efficiency of 1% aethonium gel for the treatment of various traumas of mammary gland and udder mammillars of cows. Clinical recovery of animals after administration 1% aethonium gel was stated on 3,2 days earlier, than after administration of Burenushka cream in the postoperative period. Healing and restoring action of 1% aethonium gel for udder tissues was proved by changes in number of somatic cells in milk. The quantity of somatic cells in 7 days after administration of 1% aethonium gel came back to the level which was typical healthy animals, while in the control group the quantity of somatic cells per 1 ml of milk did not decrease essentially.

In the conditions of the Republic of Belarus there was studied the activity of hepatic specific enzymes of blood serum of bull calves of black-and-white breed in course of application of various doses of zinc-containing preparations. Application of zinc-containing preparations led to multidirectional change of activity of hepatic specific serum enzymes. Application of Zinkovet preparation in dose of 1,8 g/100 kg of live weight made it possible to essentially grade the indexes of hepatic tissue affect. In the experimental group at animals there was marked the lowering in activity alanine-aminotransferase, serum glutamic oxalacetic transaminase and gamma-glutamyl transpeptidase. At the same time, there was noted the increasing of zinc-containing enzymes activity (sorbitol dehydrogenase and glutamate dehydrogenase). All these processes were caused by zinc inclusion into the metabolic process.

In the conditions of the Republic of Belarus there were studied circadian rhythms of some haemotological and biochemical blood indexes of clinically healthy calves and calves with a respiratory syndrome. There was analyzed the efficiency of administration a new complex mineral preparation CMP for correction of internal desynchronoses in complex therapy of calves with respiratory pathologies. Diseases of calves with a respiratory syndrome were accompanied by infringements of circadian fluctuations rhythm (internal desynchronosis) of haemotological and biochemical blood indexes. Application of an antimicrobial preparation Ampicillin for treatment of respiratory diseases of calves promoted the recovery of calves. Introduction of CМP preparation into therapeutic regimen of calves with respiratory syndrome proved to be rather effective; it promoted the correction of metabolic desynchronoses which accompanied the basic disease. Combined application of CМP and Ampicillin made it possible to speed up the clinical recovery of calves and on 30% to prevent animal mortality.

In the conditions of the Republic of Belarus there was studied the nonspecific resistance of lambs of Latvian Black Face breed during the colostrum and milk fed period of their growth development. In course of the experiment there were used 10 newborn lambs. Analysis of resistance was realized in accordance with a scheme: before colostral milk sucking; in 6, 12, 24 hours; in 3, 7, 14, 21 days; in 1, 2 and 3 months after birth. In lambs during the colostrum and milk fed period of growth there were marked two critical periods, which were characterized by low indicators of resistance: before colostral milk uptake and at 7-21 day-old age. Increasing of leukocytes, bactericidal, lysozymic activity of blood serum, phagocytal activity of leukocytes, crude protein and antibodies in the first days of lamb life took place due to their entrance in blood with colostral milk, just because at this time the intestines wall possessed ability to transit in native condition the antibodies, enzymes, and leukocytes. At 7-21 day-old age in connection with reduction of these factors quantity of in colostral milk, and also due to reduction of intestines capacity, their was stated that their entrance in blood of newborn lambs decreased, but at 3 month old age of lambs there were stated to form internal protective factors of resistance because of which their quantity in blood started to increase.

In the conditions of the Republic of Belarus there was studied the influence of various doses of dolomite on productivity, egg quality and a mineral metabolism of laying hens. The research was realized by an example of laying hens of Highsex Brown. The experimental hens at the age of 250 days old were divided into 4 groups on 60 heads in each by means of analog method. Laying hens of the first (control) group were fed with a basic diet including 5% of a soya cake (cockle-shell), and hens of the second, third and fourth (experimental) groups instead of a soya cake were fed with a mixed fodder with addition of a mineral additive of dolomite. Hens of the second group were fed with the additive at a rate of 2%, the third group - 3%, and the fourth group - at a rate of 5% of weight of dry matter of forage. During the experiments there were maintained optimum parameters of microclimate, recommended temperature and light regimes and a sufficient ultra-violet irradiation. As a result of the realized research it was established, that use of the mineral dolomite additive in feeding of laying hens proved to be possible as a substitute of an expensive import cockleshell. Use of various doses of dolomite promoted improvement of mineral metabolism, increasing of productivity and improvement of egg quality of laying hens.

In the conditions of the Republic of Belarus there was studied the influence of various doses of kizelgur on metabolic processes and natural resistance of poultry by an example of lying hens. Use of the mineral additive rendered the positive influence on protein, carbohydrate, lipidic and mineral metabolism in hens. It was marked that in blood the content there was an increasing of crude protein on 11,5-11,7% (Р less than 0,05), crude lipids - on 1,9-5,3%, glucose - on 25,1-54,6% (Р less than 0,01), calcium - on 0,8-12,4%, phosphorus - on 8,9-15,9%, iron - on 9,2-24,6% (Р less than 0,01) and magnesium - on 9,3-21,6%. The laying hens which were fed with the mineral kizelgur additive were characterized by better resistance reactions. Bactericidal activity of blood serum of the experimental hens was higher on 2,7-15,3% (Р less than 0,01), lysozymic activity - on 1,3 22,5% (Р less than 0,05).

In the conditions of the Republic of Belarus there was studied the yielding capacity and quality composition of nontraditional high-energy crops (sorghum and Sudan grass hybrid; millet (Panicum); white panicum (Japanese millet)) as well as there was developed a technology fodder conservation. In course of the study there was analyzed accumulation of nutrients in accordance with crop development phases and their quality composition; also there was determined a method of application of grass stands of the studied crops for their production use. It is established, that the most suitable for conditions of Vitebsk region from high-quality cultures is sorgho-sudan-grass hybrid which reaches phases of seed formation and provides productivity of dry matter more than 9 t/ha with humidity of green mass of 69% that is optimum for preparation of tinned forage. Sugar sorgho and grain is reached by phases of ear formation and have provided productivity of green mass of 25,9-25,7 t/ha, dry matter - 3,5 t/ha. To use double-cut sorgho-sudan-grass hybrid on a silo less effectively as the received green mass has high humidity (92%), and the general gathering of dry matter twice more low, than at single-cut use. At single-cut use the culture reaches phases of grain formation in which contains about 31% of dry matter that is favorable for conservation. Double-cut use of sorgho-sudan-grass hybrid is comprehensible at its cultivation in the green conveyor to use as green top dressing during the pasturable period. Japanese millet is better to use double-cut as it has provided the maximum productivity of green mass of high quality (63,9 t/ha) and dry matter (9,1 t/ha), it is in 2,3 and 1,6% of time above, than at single-cut use. Single-cut crops of sorgho-sudan-grass hybrid are expedient for using as a component at siloing of galega orientalis. In an early phase of development (7-8 leaves) the new-mown green mass of sorgho-sudan-grass hybrid possesses toxicity on the bottom border of average degree, but in 2 hours after mowing the forage becomes not toxic. In later phase of development there is an accumulation of sugars, and new-mown mass of sorgho is nontoxical. Sorghum cultures contain high percent of non-decomposed protein - 58,3-84,6% that is very important in feeding of highly productive cows.

In the conditions of the Republic of Belarus there was realized a cultivation of pasteurellas by different methods in Hottinger broth in 37 deg C temperature in course of 24 hours. Tissue culture properties were studied in accordance with the character of bacteria growth in liquid nutritive media and at the agar surface. Research results showed that in 7 hours after cultivation in media with application of shuttel apparatus and addition of glucose it was possible to obtain the highest quantity of viable pasteurellas with a high degree of virulence. The obtained culture on the basis of obtained results was proposed to be used for the production of virulence antigen.

In the conditions of the Republic of Belarus there was studied the application of sodium chloride obtained by electrolysis method on Akvamed installation in a complex of activities for the preventive measures of animal helminthoses. Electrochemical activation of aqueous solution of sodium chloride proved to be a progressive and rational technology which made it possible to substantially reduce the material costs and power consumption for the development of highly efficient and ecologically safe disinvasion solution. Application of sodium chloride solution with the minimal content of available chlorine of 3,0 g/l provided the death of 94-95% of Taeniidae eggs in course of 30 minutes after applicated of the preparation on the treated surface. The proposed method can be recommended as the most efficient and economically effective for the disinvasion of external environment.