The study of the influence of aqueous and hydro alcoholic extracts of Tinospora cordifolia on human mammary tumor cell line MCF-7 is a common way of discovering potential therapeutics for treating people suffering from hormone-dependent problems and diseases. In the present study, the cells were treated with the extracts at three different doses viz., 200 μg/ml, 400 μg/ ml and 600 μg/ml. Both the extracts produced degenerative changes in the cell in dose-dependent manner with maximum effect being noticed at the dose level of 600 μg/ml. Thus, these findings suggest that the extracts from Tinospora cordifolia have potential for acting as an antiproliferative agent in mammary tumour.

The squat lobster, Munidopsis cylindrophthalma (Alcock, 1894) was recorded for the first time from the Indian main land coast while investigating the biodiversity of the squat lobster of Gulf of Mannar during April, 2013. One specimen of the said species was collected as an incidental by-catch in the deep sea trawl fisheries off Thoothukudi coast of Gulf of Mannar, between 08º 35’ 22.5" N lat. 78º 27’ 40.9" E long and 08º 31’ 91.2" N lat. 78º 25’ 32.7"E long at a depth of 305-310 m. The present records show its extended distribution from Gulf of Mannar to east of Andamans and further to South China Sea. 

The present investigation was carried out on 25,499 weekly test day milk yield records of first lactation pertaining to 593 Sahiwal cows spread over 49 years located at National Dairy Research Institute, Karnal, India. The comparison of three lactation curve models viz, quadratic model, gamma type function and mixed log function was made in the present investigation. Mixed log function described the best fit with highest coefficient of determination (97.9%) with lowest value of root mean square error (0.025 kg) value. The peak yield of 8.08 kg in 8thweek of lactation was observed by mixed log function. The closeness of the curves of mixed log function and gamma type function with the observed lactation curve was of the same order of magnitude. The least coefficient of determination (77.8%) was observed in quadratic model with maximum root mean square error (0.081 kg). The gamma type function when compared to mixed log function, explained low peak yield and it is recommended that this function can give best fit for the low yielding cows.

The present study was conducted to elucidate the growth performance changes in Wistar rats given cadmium chloride in different doses at various intervals. Wistar rats (n=12/group) were divided into four groups viz, group I (Control) given normal drinking water whereas group II, III and IV rats were given CdCl2 @ 100, 250 and 500 ppm, respectively for 12 weeks. Animals of all the groups were closely observed through out the period of experiment thrice a day for clinical signs. Daily Feed intake (FI), Body Weights (BW), Body Weight Gain (BWG) and Feed Conversion Ratios (FCR) were recorded. Clinical signs observed upto first 5 weeks were less prominent in all the treatment group rats. After 5 weeks PE, rats of all treatment groups showed varying degree of toxic signs, which included inappetence, dullness, weakness, depression, lethargy, reduced feed intake, decrease in body weight, poor fur condition, loss of hair, change in behaviour, disinclination to move, increased thirst and dehydration. In addition, group IV rats also showed nervous disorders from 9th week onwards. The average values of feed consumption, body weight and body weight gain were significantly lower in all treatment group rats as compared to control group rats in dose and duration dependent manner. Moreover, FCR increased significantly in all treatment groups from 4th week PE than control group rats upto the end of trial.

Campylobacter is the commonest reported bacterial cause of infectious intestinal disease. To study the epidemiology of Campylobacter infection among children, 100 stool samples along with patients anamnesis were collected from the clinical diarrheic reported to Enterology unit of Institute for child Health and centre for Children, Egmore, Chennai, Tamil Nadu between May 2013 to June 2013. Samples were subjected to traditional culture and modern PCR techniques, both of which revealed same results of 13% prevalence of Campylobacter sps (8% C.jejuni & 5% C.coli). Analyzing the patients anamnesis to study the epidemiological determinants, sex has a significance (P<0.05). Age and residential area have no significance and summer season and cross contamination could be probable determinants for the infection.

Data relating to 130 sows, 19 boars from 400 farrrowings spread over a period from 1984 to 1992 were utilized to study genetic and non-genetic effects in variation of litter size and weight at birth and at weaning. The overall mean litter size at birth (LSB)was 6.83 ± 0.13 piglets. The effects of period, season of farrowings and inbreeding on litter size at birth were not significant (P>0.05).The overall least squares mean of litter size at weaning(LWW) was 4.83 ± 0.12 and was significantly (Pd”0.05) affected by in breeding. Litter weight at birth (LWB) had a least square mean of 7.81 ± .16 kg and it was significantly (Pd”0.05) affected by period of farrowing. The mean LWB of non-inbred sows was 8.22 ± 0.19kg and that of inbred sows was7.41 ± 0.29 kg. The overall least squares mean for litter weight at weaning (LWW) was 39.36 ± 1.25 kg and inbreeding of sow exerted significant effect on LWW. The LWB and LWW were significantly affected by period of farrowing. The litter size at birth and at weaning and litter weight at birth and at weaning was not significantly affected by season of birth. The heritability estimates of litter size at birth and litter size at weaning were 0.096 ± 0.09 and 0.816 ± 0.27 respectively. The corresponding heritability values for LWB and LWW were 0.41 ± 0.18 and 0.53 ± 0.21 respectively. 

In animal breeding, genetic disorders are one of the most important issues for breeders. The present study was carried out to genotype HF crossbred cattle for FXI deficiency and CVM using PCR and PCR-RFLP using 50 blood samples. Amplicons of 244 bp for FXI gene and the 287 bp for SLC35A3 gene were successfully amplified. Analysis of amplicons of FXI gene revealed single 244 bp fragment which indicates absence of mutant allele. The amplicons of 287 bp of SLC35A3 gene was digested with Pst I RE which revealed two fragments of size 264 bp and 23 bp  for normal animals. In the present study, out of fifty HF crossbred animals screened neither carrier nor affected animals were found for FXID and CVM.

The research was carried out to study the effects of dietary supplementation of Tulasi (Ocimum sanctum) and selenium on ALT and AST enzyme levels in broiler chicken. A total of forty-two broiler chicks of day old divided into six groups of seven each were used for this study. Ocimum sanctum leaf powder (0.25% and 0.5%), organic selenium (0.3 ppm) and their combinations were added to the basal diet. Body weight and feed consumption were recorded at weekly intervals. Blood samples were taken at the end of 6th week for enzymological assay from each treatment. The enzymes assayed were alanine transaminase (ALT) and aspartate transaminase (AST). Dietary supplementation of Ocimum sanctum leaf powder at 0.25%, 0.5% levels and its combination (0.5% level) with selenium (0.3 ppm) reduced the levels of ALT and AST significantly (P<0.05). It was concluded that Tulasi (Ocimum sanctum) has hepato-protective properties.

The gross studies on the hippocampus were made on 10 specimens each of calves and adults of the Indian buffalo. The hippocampus was a curved elevation, lying immediately ventral to the splenium of the corpus callosum, dorsal to the lateral aspect of the thalamus. It occupied the floor of the inferior horn of the lateral ventricle. The ventricular surface of the hippocampus was covered by a thin layer of white matter, the alveus. Rostrolaterally the alveus joined a thick fibrous band, the hippocampal fimbria which connected the alveus to the fornix. On the ventromedial aspect, a deep groove, the hippocampal sulcus, separated this surface into lateral and medial portions. 

A study was conducted to analyse the migratory sheep production system in southern agro-climatic zone of Tamil Nadu. Reproductive performance of the rams and ewes was recorded through the questionnaire both in migratory and non-migratory flocks. Mean lambing percentage, twinning percentage, livability at birth percentage, age at first mating (months) in ewes, age at first mating (months) in rams, age at first lambing (months) and weaning percentage in migratory and non-migratory flocks were 93.56 and 91.50; 1.87 and 1.52; 98.32 and 98.73; 12.34 and 13.22; 19.64 and 21.44; 18.54 and 19.68; 85.98 and 87.15, respectively. The weaning period for ram and ewe lambs were 2.94+0.96 and 5.03+0.13 in migratory flocks and 4.82+0.13 and 6.06+0.17 in non-migratory flocks, respectively. Reproductive performance of sheep in migratory flocks was significantly better than nonmigratory flocks. The months of October,  November and December were main lambing season and the months of April and May were second lambing season.