Avian metapneumovirus (AMPV) is a worldwide an acute, extremely contagious upper respiratory illness in Turkey. Chickens may also be affected with virus and cause Swollen Head Syndrome. Sometime it is associated with reproductive affection. The disease's first disorder appeared in late 1970 in South Africa, where 6 subtypes (A, B, C, and D) and 2 additional subtypes were found. The virus belongs to the family Paramyxoviridae, genus Metapneumovirus. . Both of systemic and local immunity may be developed but there is no relation of maternal immunity for produce production. The disease causes an important economic loss due to decrease in egg production and bad egg shell quality. The disease spread between birds rapidly and a wild birds may be infected and paly role in transmission of the disease Also in turkey there is no specific clinical signs and lesion and while the most effective methods to detection are Elisa and (RT-PCR) carry out the disease diagnosis. Biosecurity programs of vaccination are effective for controlling of disease. Both of alive attenuated and inactivated vaccines are useful for provide a good protection against the disease While, new vaccines were developed to avoid infection.

Contagious ecthyma is an important viral disease infect animals' skin mostly small ruminants, it could infect other ruminants with a zoonotic pattern. In dromedary camels of Basrah province, Contagious ecthyma was detected and diagnosed. Seventy-eight local dromedary breeds, 2-6 years old show clinical manifestations of Anorexia and difficulty grazing, lesions of Contagious ecthyma appear as papules, vesicles, and scabs located at the upper and lower parts of the lips, commeasure and /or around the mouth, Furthermore, Lesions in the form of Fissures with lips edema was also detected on diseased camels.   Twenty, clinically healthy dromedaries served as controls. The infection was confirmed using the PCR technique.  Blood parameters with acute phase response have been also evaluated. Results indicated that diseased camels show different clinical manifestations belonging to contagious ecthyma with a significant increase in body temperature, heart and respiratory rate, Moreover, Leukocytosis due to lymphocytosis was detected in infected dromedaries. a significant increase in ESR was detected in infected dromedaries compared with controls. Results referred to an increase in haptoglobin and Fibrinogen in diseased dromedaries with contagious ecthyma compared to controls. The contagious ecthyma of camels was still circulating in Iraqi areas, where appropriate preventive measures must be taken to prevent the spread of disease among camel herds and reduce the resulting economic losses.

Paratyphoid infection is a serious-infectious disease of poultry with economic and public health consequences. We investigated paratyphoid Salmonella infections and their associated histopathological changes in broiler chicks in Sulaymaniyah province using molecular, histopathological and immunohistochemical techniques. A total of 130 broiler farms, aged between 1 to 20 days were investigated. The results showed that the prevalence of paratyphoid Salmonella in the region was 28.5%, including Salmonella Enteritidis (70.3%) and Salmonella Typhimurium (29.7%). The rate of infection was higher (76%) among 1-10 days-old chicks in comparison to 11-20 days-old chicks (24%). The distribution of the pathogen was varied among the tested organs, including the caecum (97.3%), liver (91.9%) and yolk-sac (86.5%). The rate of infection by S. enteritidis in 1–10-day-old chicks in the organs was higher (67.9%) than the rate of infection by S. typhimurium in the liver (25%), yolk-sac (25%) and caecum (28.6%). There was a highly significant positive correlation between S. enteritidis and S. typhimurium infections in the liver (r=0.818, P=0.000, n=37). At the same time, a highly significant strong negative correlation between S. enteritidis and S. typhimurium infections was found between the inspected organs. The most obvious pathological changes were degeneration and necrosis of the hepatocytes and sloughing of the caeca epithelium. Claudin-1 expression and distribution among cellular compartments were mostly affected by Salmonella enteritidis-positive cases. The findings of this study showed that there was a widespread paratyphoid Salmonella infection in the region, and associated with severe histopathological and immunohistochemical changes, especially among 1-10 days-old chicks.

Influenza A viruses spread naturally among aquatic birds, especially the wild ones. The aim of the current study is to investigate the avian influenza virus subtype H9N2 in the wild and domestic ducks in different geographical areas of Basrah Governorate, namely Shatt Al Arab, Abu Al-Khaseeb, Az Zubayr, and Al Qurnah. The presence of the virus was initially investigated generally using a pair of universal primers by performing the reverse transcriptase polymerase chain reaction. Subsequently, the virus subtype H9N2 was detected in both bird species. The results showed that the overall prevalence of the virus, regardless of subtype, was 66%. The total percentage in wild ducks was 78.6%, which showed significantly higher values than what was in domestic ducks, where it was 52.8%. Regarding the spread of the virus according to geographical location, the percentage of viruses in wild ducks was comparable in all areas involved in the study, while in domestic ducks it was higher in the Al Qurnah region, northern Basrah Governorate, compared to the rest of the regions.

The aim of this study was to look into the toxicity of captopril and enalapril in high doses in the liver. The animals in this experiment were divided into five groups of ten each, with the first group serving as a control group, receiving only distilled water, the second and thrird groups receiving doses of captopril 10 and 20%, and the fourth and fifth groups receiving doses of enalapril 10 and 20%. The dose is taken orally once every three days for four weeks. After one week, samples were collected, and then again four weeks later. After one week of treatment with Enalapril 20%, biochemical testing revealed significant elevations in ALT and AST. After 1 and 4 weeks of treatment with Enalapril 20%, there was a decrease in glutathione and an increase in malondialdehyde, whereas captopril 20% and Enalapril 10 and 20% significantly raised malondialdehyde levels. Rats given captopril 20% revealed diffuse vacuolar degeneration. The 10% Enalapril group experienced similar symptoms, however the 20% Enalapril group experienced vacuolar degeneration, coagulative necrosis, significant inflammatory cell infiltration, portal vein congestion, and sinusoidal dilatation. The researchers looked at the expression of TNF-a in the livers of rats after four weeks of therapy with Captopril 10% and 20% and Enalapril 20% (20%). The results revealed three levels of expression: low, medium, and high. According to the findings of this study, Enalapril has higher adverse impacts on the liver than captopril at the same dose ratio.

Gastrointestinal parasites (GIP) are often associated with diarrhea in buffaloes, which affects health, growth, and production. They are also sources of infestation in the herd, nearby herds, and grazing areas. The current study aims to diagnose the different types of GIP that infect buffaloes in the Mosul city, Iraq, and to determine their infestation rate. A total of 100 fecal samples were randomly collected from buffaloes of different ages (ranging from 1.5 to 5 years old) and both sexes in various regions of Mosul city. These samples were examined using direct smear technique, with or without iodine dye, flotation method, and sedimentation method, with or without methylene blue dye, between September 2022 and February 2023. The overall infestation rate with GIP was 59%, comprising intestinal protozoa (56%), Nematodes (6%), and Trematodes (2%). That included Buxtonella sulcata (56%); Trichostrongylus spp. (3%); Haemonchus spp. (1%); Cooperia spp. (1%); Ostertagia ostertagi. (1%); and Fasciola hepatica (2%). Moreover, a variation in the infestation rates according to the months of collected samples was observed; significantly (P<0.05) highest infestation rate was recorded in February at 93.3%, followed by November at 82%, and the lowest infestation rate was recorded in October and September at 16% and 36.3%, respectively. In conclusion, the highest infestation rate with GIP in buffaloes in the city of Mosul, Iraq, this must be given increased attention by owners and veterinarians for strategical control of these parasites. 

Obesity is a metabolic condition that causes people to develop a variety of diseases and has emerged as a serious global public-health problem. Tocotrienol, a member of the vitamin E family that comes from the annatto bean (Bixa orellana), is special in that it doesn't contain alpha-tocopherol and instead mostly consists of delta-tocotrienol (approximately 90%) and gamma-tocotrienol (about 10%). This investigation aimed to ascertain whether annatto tocotrienol could improve certain biochemical indicators and metabolic hormones in male rats fed a high-fat diet. Eighteen adult male rats in total were split into three groups randomly (6 for each). Control group was given a diet low in fat (LF 10 % kcal from fat), High fat diet (HFD) group was fed with high fat diet (HF 60 % kcal from fat), And high fat diet with tocotrienol (HFDT) group was fed with high fat diet additive tocotrienol (60 mg/kg) dissolved in olive oil (1ml/kg) for 12 weeks. Tocotrienol treatment led to a significant decrease in total protein and globulin compared with the high-fat diet group and it significantly increased HDL-C compared with rats fed on a high-fat diet and control groups. While, tocotrienols significantly reduced the level of LDL and insulin hormone in the High fat diet plus tocotrienols group compared to the other groups.

The gastrointestinal tract provides the biological environment for nutrient digestion and absorption. Its physical and chemical barriers are crucial to protect from invading pathogens and toxic substances. On this basis, the intactness of the gastrointestinal tract, with its multiple functions and impacts, is one of the key prerequisites for human and animal health. Undoubtedly, the functions of a healthy gut system also largely benefit the welfare and performance of animals in farming systems such as poultry industries. Broiler chickens grow rapidly, as a result of rigorous genetic programs, due to the high absorption capacity of intestinal epithelia for nutrients, the quick transport of nutrients to the muscle, and their efficient conversion into energy and biomass. Due to oxygen metabolism or enteric commensal bacteria, intestinal epithelial cells create reactive oxygen and nitrogen species physiologically. However, increased generation of these oxidants goes along with the formation of free radicals resulting in oxidative stress causing lipid peroxidation and dramatic molecular changes in the structure and function of the cell and mitochondrial membranes. These effects contribute to chronic oxidative stress and inflammation of the gastrointestinal tract and generally affect all chicken organs, tissues, and cells. Hence, all forms of chronic stress, regardless of the origin, negatively impact the chicken's overall performance, health, and welfare. This review article highlights some enteric inflammation models and biomarkers to evaluate gut integrity in chickens and discusses the repercussions that chronic stress and intestinal inflammation have on the health and performance of commercial poultry.

The presence of microorganisms is one of the major factors affecting the quality of smoked fish sold in the open markets. Smoked blue whiting fish (Micromesistius poutasou), commonly called (Panla) sold in the Odeomu market in Osun State, were analyzed for microbial contaminants. Isolates were identified using conventional biochemical methods, and antibiotics susceptibility testing was carried out using the disc diffusion method. The total bacterial counts (TBC) results showed that the fish samples had high bacterial counts, ranging from 2.1×103 to 9.2×103 colony-forming units (CFU)/g. Bacteria isolated from the fish samples were: E. coli (45.46%), Enterobacter spp. (1.01%), Klebsiella spp. (6.06%), Proteus spp. (9.09%), Salmonella spp. (7.07%), Shigella spp. (19.19%), Bacillus spp. (4.04%) and Staphylococcus spp. (8.08%). The antibiotic sensitivity pattern of Gram-Negative bacteria indicated that all the isolates were resistant to more than three antibiotics. All E. coli isolates were resistant to augmentin and ceftazidime, 82.2% were resistant to cefuroxime, 17.7% to gentamicin, and 6.7% to ofloxacin. Screening of resistance genes showed that all six selected multiple antibiotic-resistant E. coli isolates tested harbored TEM gene, and two isolates (33.33%) harbored the aac (3)-II gene. None of the isolates harbored SHV, CTX-M, and qnr B genes. Our results showed that smoked blue whiting fish may pose a significant risk of spreading antibiotic-resistant bacteria that contain multiple antibiotic-resistance genes, highlighting a serious public health concern

In order to evaluate the infection of veterinarians by brucellosis in Algeria and to study the associated epidemiological factors, we created a survey consisting of 21 questions that was distributed in paper and digital versions. We collected responses of 100 veterinarians. The survey revealed that 15% of the veterinarians got infected with brucellosis during their practice. Almost half (47%) contracted the disease through direct contact with diseased animals and/or their products, mostly during intervention for retained placenta (75%); 20% became infected during vaccination campaigns against brucellosis, due to unprotected hands, where13% were infected through consumption of raw milk. Factors such as the frequency of encountering brucellosis farms, negligence in wearing protective equipment, lack of training in handling the vaccine, as well as lack of work hygiene were reported by these professionals.