On the basis of analysis of literary sources and realized studies there was realized an evaluation of the degree of losses caused by ruminant monieziasis in the conditions of modern agricultural production in the Republic of Belarus; the strategy of medical and preventive measures was presented. In course of studies there were analyzed sheep and cattle of different classes bred in farm holding of Belarus and imported from abroad, as well as different anthelmintic agents. Studying of antihelminthefficiency was tested on lambs with body weight 20 kg. Lambs were infested with moniezia (Moniezia expansa). Analysis of anthelmintic agent Alverm efficiency was realized by the example on infested heifers. Albazen was administrated once in dose of 0,8 mg/1 kg. Prazikvantel was administrated once in dose of 5,0 mg/1kg. Alverm was administrated once in dose of 80,0 mg/1 kg. Research results showed 100% extencefficiency and intencefficiency of albazen and prazikvantel. Alverm administrated once in dose of 80,0 mg/1 kg gly had 100 % 100 % extencefficiency and intencefficiency

Development of new compositions of premixes for cows with milk yield of 4-5 thousands kg per lactation depending on lactation stage and pregnancy was realized in the conditions of the Republic of Belarus. Efficiency of application of premixes in comparison with the standard ones was estimated. Experiment was realized by an example of 3 groups of cows of white-and-black breed; experimental period included beginning milking period (90 days) and the main lactation period (142 days). Cows of the first control group were given premix P60-6M with combined feed. Animals of the second group were fed with premixes created on the basis of carotene and microelements content. Cows of the third group were given premixes in accordance with recommended standards. The refined standards of cow vitamin and trace elements consumption were presented. Formulas of premixes for high-producing cows were presented. The research results showed that the developed formulas corresponded to the physiological needs and their application influenced on metabolism and milk producing ability. Application of experimental premixes made it possible to increase the digestibility of nutritive substancesoin 2,3-7,5%. Application of vitamins and trace elements in heightened doses (on 10-30%) caused the increasing of their uptake and increasing of cuprum, zinc, manganese and cobalt content in blood on 11,6-40,8%

Studying of efficiency of application of a natural biological control agent BioLAD obtained as a result of cultivation of Fusarium sambucinum fungus in feeding of broiler chickens was realized in the conditions of the Republic of Belarus. There were studied 100 broiler chickens of Ross-308 cross. Broiler chickens of the first (control) group were fed with standard diet with PK-5-1. Broiler chickens of the experimental groups starting from one day old age till the end of the growing period (41 days old) were fed with feed supplement BioLAD in different doses: 0,25 ml/head (second group), 0,5 ml/head (third group), 1 ml/head (fourth group). Research results showed that natural biological control agent BioLAD in dose of 0,5 ml/head made it possible to increase chicken live weight on 11,2 %, viability - on 4,2%. Feeding charges per 1 kg of live weight gain were1,89 kg (second group), 1,81 kg (third group), 1,90 kg (fourth group). It made it possible to decrease the combined feed charges on 6,4% (second group), on 10,4% (third group), and on 5,9% (fourth group). Application of biological control agent BioLAD had an effect on poultry growth activity, promoted high level of chickens viability, increased the indices of general and local protection, stimulated metabolic processes

Determination of influence of combined feed with carnitine and 3% lipids on digestibility of nutrients in ration of fattening stores was realized in the conditions of the Republic of Belarus by an example of 8 castrated male pigs of Belarusian meaty breed with body weight of 60-65 kg. Piglets were divided into 2 groups in accordance with analogue pair principle. Selected animals were kept in single cages specially equipped for fecal and urina gathering. Both groups of animals were given the same combined feed SK-26 which included 3% lipids. Experimental piglets were fed with combined feed with carnitine in dose of 50 g/t of mixed fodder. The mixed fodder contained the following ingredients: wheat; triticale; grain mixture; sunflower oil cakes; liprot SG; tricalcium phosphate; calcium carbonate; salt; premix KS-4; vegetable oil. Research results showed that enriching of combined feed carnitine rendered positive influence on digestibility and absorbency of nutrients. It made it possible to increase the digestibility of dry matter on 2,1%, organic matter on 2,0%, crude protein on 3,1%, crude fat on 7,4%, crude fiber on 8,6%, free-nitrogen extract on 1,1%, as well as to increase nitrogen, calcium and phosphorus absorbency. Quantity of saved nitrogen in the experimental group (with carnitine additive) was on 21,1% than in control one. Quantity of saved nitrogen and absorbed with feed was on 9,8% and 5,6% respectively higher than the same indexes for the control group; calcium - on 15,5% and 2,6%, phosphorus - on 23,3% and 3,7%, respectively

Japanese millet (Echinochloa frumentacea) growing and yielding capacity was estimated in single and mixed sowings cultivated on sod-podzolic light loamy soils in the conditions of the Republic of Belarus; as well as comparative evaluation of silage quality and determination of digestibility of nutrients. Field experiment with forage crops was realized in threefold replication in accordance with the following scheme: Japanese millet (100%); Japanese millet (70%) + vetch (Vicia) (30%); Japanese millet (70%) + lupine (Luoinus) (30%); Japanese millet (70%) + pea (Pisum) (30%); Japanese millet (70%) + soybean (Glycine max) (30%). Research results showed that mixed sowings of Japanese millet with bean cultures made it possible to obtain higher yields than single sowings on 5,9-15,6%. Silage made of Japanese millet with bean culture contained higher amount of crude protein on 2,73-3,98% in comparison with silage which was produces only from Japanese millet. Silage produced from Japanese millet mixture with high protein crops had high energy and protein value: 0,90-0,92 fodder units; 9,47-9,59 mJ of metabolic energy per 1 kg of dry matter and 102-103 g of digestible protein per 1 fodder unit

Investigation of influence of probiotic Dialact and immunostimulant Alveozan on digesting of nutritive substances by broiler chickens of Kobb-500 cross, as well as control over their individual development were realized in the conditions of the Republic of Belarus. The first (control) group of chicken was given standard well-balanced ration. Chickens of the second group were administrated immunostimulant Alveozan in dose of 10 mkg/kg of live weight with drinking water once a day in course of 5 days, with 10 days interval till the end of the growing period. Chickens of the third group were administrated preparation Dialact in dose of 0,1-0,2 ml with drinking water once a day in course of 3 days, with 14 days interval till the end of growing period. Chickens of the fourth group were given Alveozan in dose of 10 microgram/kg of live weight once a day in course of 5 days with 10 days interval, and Dialact in dose 0,1-0,2 ml once a day in course of 3 days, with 6 and 14 days interval. Research results showed that complex application of probiotic Dialact and immunostimulant Alveozan increased the viability of chickens on 100%, average live weight - on 5,1%, average daily weight gain - on 5,1%. Administration of Dialact and Alveozan, both separately and in complex, increased the digestibility of nutritive substances of mixed fodders: application of nitrogen increased on 1,93-6,38%, application of calcium decreased on 10,41-12,54%, phosphorus use increased on 2,38%

Elaboration of production technology of rape (Brassica napus) phospholipids as one of components of feed additive was realized in the conditions of the Republic of Belarus. The following equipment was used for rapeseed processing: conveyer screw for seeds, conveyer for pressed seeds (seed cake), press Farraet Zralok LC preliminary, press - Farmet Zralok PL finishing, storage-capacity for oil, storage with mixing mechanism, automatic leaf filter, compressor, air vent, air filter. Rape oil was the main product of rape processing and oil seed press cake and rape phospholipides were the additional products. Quality indexes of rape phospholipids (appearance; quantity of obtained phospholipids; moisture content; dry matter content; oil and extractive matter content; total amount of carbohydrates) were analyzed. Results of phospholipids production depending on period of filtration and pressure load in the process of oil filtration were presented. Results of rape phospholipids production depending on air pressure were given. There were obtained the following optimal parameters for phospholipids production: optimal filtration time of freshly squeezed rape oil – 5-6 hours; optimal pressure load of during the filtration of raw rape oil - 2,5-3,0 atmospheres; and optimal air pressure during the filter drying - 2,5-3,0 atmospheres. The proposed production technology of rape phospholipids made it possible to produce 4,5-5,5% of phospholipids from 1 kg of rape

Determination of productivity and natural resistance indexes of laying hens after application of dry multienzyme preparation Vitazim (xylanase, 3600 units/g; cellulose, 3000 units/g; beta-glucanase, 7000 units/g); as well as the specification of optimal doses the enzyme were realized in the conditions of the Republic of Belarus. Research results showed that the best indexes of egg yields of laying hens were obtained after application in the main poultry diet of enzyme preparation Vitazim in dose 500 g/t that made it possible to increase the productivity in the experimemtal group on 12%. Application of Vitazim also promoted the increasing of natural resistance level of laying hens. There was stated the positive effect of Vitazim on bactericidal activity of blood serum. Before the beginning of test this index was the level of 44,35+/-0,92 – 56,52 +/-1,63. By the 300-th day of life the bactericidal activity of blood serum in experimental group administrated Vitazim in dose 300 g/t exceeded the control idexes on 3,8%; in the second experimental group (Vitazim in dose of 500 g/h) – on 29,5%; in the third experimental group (/vitazim on dose of 700 g/h) – on 23,7%.Vitazim administration also exercised positive influence on lysozyme activity in blood serum of lying hens

Factors which increased milk productivity (age and continuance of service period) were studied in the conditions of an educational establishment of the Republic of Belarus by an example of cows of black-and-white breed. Dynamics of growth of milk productivity in course of 8 research years was presented. Analysis of interrelation between cow productivity and cow age was given. Mathematical calculation of relations between cow productivity indexes (milk yield, fat content, butter fat) and service period duration was given. Research results showed that increasing of an average term of economic use of cows and decreasing of duration of service period up to 90 days made it possible to increase dairy effiiemcy and herd reproduction, as well as obtain higher economic efficiency

Analysis of influence of boar genotype by MUC4 gene on viability of progeny was realized in the conditions in the Republic of Belarus, as well as the evaluation of possibilities of association of polymorphic variants of gene with fattening and meaty qualities of obtained from the boars progeny were conducted. In course of studies there was analyzed the polymorphism of MUC4 gene at producer boars of studied breeds. There was revealed high occurring frequency of desirable allele MUC4**c and MUC4**cc genotype in all studied populations. Boars of Belarusian Meaty breed with genotypes MUC4**cc by MUC4 gene authentically (P less than 0,01) exceeded boars with genotype MUC4**cg according to piglet viability indexes at weaning period on 5,6%. For the further evaluation of the potential role of MUC4gene in marker selection there was realized determination of relations between genotypes of studied marker and other economic traits of swine (fattening and meaty traits of boar progeny). There was stated the authentic increasing of fattening and meaty traits of stores obtained from boars with homozygous genotype MUC4**cc in comparison with progeny fathers of which in their genotype had mutant allel MUC4**g. For the forecasting and modeling of genotypes resistant to colibacillosis there was presented a scheme of selection boars and sows of different genotypes by MUC4 gene for the increasing of progeny viability. According to the scheme the preferred selection was MUC4**cc x MUC4**cc. This selection was recommended for the self-replacement and creation of nuclear stock