A comparative study to assess the quantity and quality of milk production in milch cattle using TANUVAS and Commercial (AGRIMIN® FORTE) mineral mixture was conducted in two dairy farms in Ramanathapuram district in the form of On Farm Trials (OFT). Three animals in the same stage of milking were selected from each farm. The animals were divided in to three groups viz. A, B and C with one animal in each group. All the animals were in the same plane of nutrition in the particular farm. Group A was kept as control, Group B supplemented with TANUVAS mineral mixture and animals in Group C were supplemented with AGRIMIN ® FORTE and the study was conducted for a period of 4 months. Although both the treatment groups (B and C) showed elevation in volume of production and fat % and the rate of raise in fat % was found to be higher in group B and the amount of raise in volume of milk produced was found to be higher in group C. The SNF % and Protein % were found to be increased only in group C.

Polycystic ovarian syndrome (PCOS) is a combination of endocrine and metabolic syndrome contributing to both the terms as a clinical feature in women. The present study was conducted to find the alleviative effect of aqueous extract of Asparagus racemosus against the induced PCOS in Wistar rats. About 60 Wistar rats (n=10) are randomly divided into 6 groups: Group 1 (control group), Group 2 (Asparagus racemosus control), Group 3 (PCOS control estradiol valerate 5 mg/rat), Group 4 (estradiol valerate + 1000 mg/kg Asparagus racemosus Prophylactic treatment from day 1 of induction of PCOS), Group 5 (estradiol valerate + 100 mg/kg Asparagus racemosus treatment, after induction of PCOS), Group 6 (Metformin 100 mg/kg). Haematological parameters such as glucose, total protein, albumin, ALT, AST, ALP, triglycerides, cholesterol, C reactive proteins, BUN and creatinine were studied in polycystic ovarian syndrome. Metformin group showed highly significant (P<0.01) reduction in haemoglobin, Packed Cell Volume (PCV) and significant (P< 0.05) reduction in Total Erythrocyte Count (TEC) compared to prophylactic, therapeutic and PCOS groups while PCOS group showed elevation in platelet count (P< 0.05). Significant increase (p < 0.05) in serum glucose, cholesterol and CRP noticed in the PCOS groups compared to prophylactic, therapeutic and metformin groups. The results indicated that Asparagus racemosus had partial alleviating effect on haemato-biochemical parameters caused by polycystic ovarian syndrome in Wistar rats.

The different parts of Murraya koenigii leaf are traditionally used for treatment of wide variety of ailments. The present study was designed to evaluate the effect of methanolic extract of curry leaves on growth and haemato-biochemical parameters in adjuvant induced arthritis. Sixty Wistar rats were divided into 6 groups containing ten each (n=10), Group I- Sham control, Group II- Plant extract only, Group III- Complete Freund’s Adjuvant (CFA) only, Group IV- CFA + ibuprofen, Group V- Prophylactic group, Group VI- Therapeutic group. Rheumatoid arthritis (RA) was induced by sub-plantar injection of Complete Freund’s Adjuvant (CFA). The body weight gain and feed intake were measured at weekly intervals upto 28th days and blood was collected on 28 day for haematology and serum biochemistry. The analysis of parameters on body weight, feed intake and haematobiochemistry revealed that curry leaf extract had a considerable effect in preventing and ameliorating the severity of arthritis. Methanolic extract of curry leaves appears to be a promising natural remedy of RA. 

Canine oral papillomatosis is a contagious and spontaneously regressing benign neoplastic disease of young dogs caused by canine oral papillomavirus. Six dogs of different breeds aged between 1-3 years were presented to Veterinary Clinical Complex with the history of wart like lesions in different parts of the oral cavity. Under Xylazine sedation and 10 % Lignocaine spray representative biopsy sample of wart was surgically excised. Autogenous vaccine was developed and mixed with formalin solution to in activate the virus. Dogs were subjected to inj. Autovaccine 1 ml through subcutaneous route once in a week for 5 weeks. Warts were completely regressed within 4 weeks period after autoimmune therapy. There was no recurrence of papillomatosis among the treated dogs during the follow-up period of 6 months and no adverse effects were recorded.

Recently calved Jersey crossbred primiparous cow was presented with history of in appetence and scanty voiding of dung for past 3 days. On physical examination vital parameters were within normal range. On per rectal examination, there was distended caecum from the pelvic inlet which extended cranially. Per rectal examination revealed distension of caecum which was extended cranially. Simultaneous auscultation and percussion on the right upper flank revealed clear metallic ping sound which extended up to 11th intercostal space on first day. Transabdominal ultrasonographic examination revealed thick semicircular echogenic caecal wall and contents on mid upper flank, extended up to 11th intercostal space. Bethanechol 0.07 mg/kg SID orally along with parenteral fluid therapy was given for 3 days. On fourth day after initiation of therapy the animal voided dung normally and recovered uneventfully.

A nine months male cat was presented with the history of itching and scratching over the face, ears and forelimb since a month. On physical examination alopecia, scales, crusty, thick, wrinkled and leathery lesions were found on the face and ears. All the vitals were within the normal range. Microscopic examination of the skin scrapping revealed Notoedres cati. Further history also revealed the presence of pruritus and cutaneous lesions on the shoulder and arm region of the owner. The cat was treated with Inj.Ivermectin @200 µg/kg along with topical application of sulphur (10%).

Leptospirosis is under diagnosed and under reported in developing countries due to lack of diagnostic facilities. The diagnosis of leptospirosis is complex, because the gold standard tests are not easily available. Though rapid tests are available for the past two decades, they have to be combined with the existing gold standard tests for confirmation of diagnosis. It should be adequate to diagnose leptospirosis with rapid tests. I intend to review the literature from developing countries in Asia, Latin America and Africa and suggest the need for utilizing rapid tests for diagnosis. Leptospirosis can be diagnosed only by diagnostic tests and epidemiological data, such as incidence/ prevalence data cannot be obtained without these tests. Without these data, funding cannot be obtained for diagnostic, treatment and control programs, as without diagnostic tests, leptospirosis would be considered a rare disease. In this article, the various guidelines for the diagnosis of leptospirosis will be discussed.

The quality and quantity of wool production is a function of number and type of wool follicles. Hence a study was conducted to evaluate the follicular characteristics of corriedale sheep, a dual purpose breed established well in the temperate climatic conditions of Kashmir valley. Skin samples of corriedale sheep were collected ethically from different body regions viz; neck, shoulder, thorax, flank and back of both sexes and preserved in 10% neutral buffered formalin. The samples were processed for histomorphlogy. Primary and secondary follicle density and their diameter was recorded. Secondary to primary follicle ratio was also calculated. The study revealed the difference in the follicular density and S/P follicle ratio between the sexes as well as between the body regions. In general, the follicle density and S/P ratio was found higher in the flank and thorax region respectively. Evaluation of the follicular profile at flank and thorax during early period will serve as a reliable predictor for the wool yield and quality. 

Bacterial infection followed by implant fixation is a common complication after surgery. In order to reduce the incidence of implant-associated infections, several biomaterial surface treatments have been proposed. In this study, the effect of in vitro antibacterial activity of magnetron sputtered silver nanoparticles was studied. Sputtering was done using radiofrequency magnetron sputtering technology. Film applicator coating assay was used to assess the antibacterial effect of the coated titanium implants. SEM examination revealed successful deposition of silver nanoparticles on the titanium surface. The average diameter of the nanoparticles was 40-60 nm. SEM examination before incubation and after incubation of bacteria was done. The bactericidal ratio between the uncoated and coated implant was determined.

Oxidative stress is a common mechanism contributing to initiation and progression of hepatic damage in a variety of liver disorders. Hence, there is a great demand for the development of agents with potent antioxidant effect. The aim of the present investigation is to evaluate the efficacy of raw and nanoforms of resveratrol and silibinin as a hepatoprotective and an antioxidant against diethylnitrosamine induced hepatocellular damage. 0.01% diethylnitrosamine administration to rats resulted in significantly elevated levels of lipid peroxidation (LPO) and decreased levels of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), glutathione reductase (GSH) and total protein (TP) in the liver tissue. Post-treatment with the nano resveratrol (50 mg/kg), nano silibinin (50 mg/kg), raw resveratrol (50 mg/kg), raw silibinin (50 mg/kg) orally for 30 days significantly reversed the diethylnitrosamine induced alterations in the liver tissue and offered almost complete protection. The results from the present study indicate that both nano forms exhibit good hepatoprotective and antioxidant potential against diethylnitrosamine induced hepatocellular damage in rats as compared to raw forms.