خيارات البحث
النتائج 61 - 70 من 525
A study of animal bones excavated from the shell mound of Jeju Jongdali 1819 archaeological site
2014
Kang, Y.H., Jeju National University, Jeju, Republic of Korea | Moon, J.H., Jeju National University, Jeju, Republic of Korea | Ahn, M.J., Jeju National University, Jeju, Republic of Korea | Bang, M.B., Jeju Cultural Heritage Institute, Jeju, Republic of Korea | Shin, T.K., Jeju National University, Jeju, Republic of Korea
Animal bones excavated with earthenware from the shell mound at the Jeju Jongdali 1819 archeological site, where three consecutive chronological layers covering the Neolithic (B.C. 15C-B.C. 10C), early Tamra, and late Tamra periods have been identified, were morphologically classified. The majority of the bones from all three periods were broken or split. The major fauna of the mammalian bones in all periods were Cervus spp., Sus scrofa, and Bos taurus. In the early and late Tamra periods, bones of small animals including Mustela sibirica coreana, Meles meles, Rodentia, and Aves were also found in small number. The excavated bones were from all parts of the animal bodies, including head, trunk, forelimb, and hindlimb. Collectively, these findings suggest that the major fauna from the Neolithic to late Tamra periods consisted of Cervus spp., Sus scrofa, and Bos taurus and that the fauna was dissected and carried to the shell mound site after hunting. Information from the bone remains in the shell mound are useful data for study of the wildlife and domestic animals living during the prehistoric period of Jeju Island.
اظهر المزيد [+] اقل [-]Preoperative administration effect of metronidazole, ceftriaxone sodium and their combination on stenotic index of jejunal anastomotic segment of dogs
2014
Rehan, Rafique., Veterinary Research Institute, Lahore, Pakistan | Asi, Muhammad Nadeem., Department of Clinical Medicine & Surgery, University of Agriculture Faisalabad, Faisalabad, Pakistan | Saqib, Muhammad., Department of Clinical Medicine & Surgery, University of Agriculture Faisalabad, Faisalabad, Pakistan | Hussain, Muhammad Hammad., Department of Clinical Medicine & Surgery, University of Agriculture Faisalabad, Faisalabad, Pakistan | Sial, Awais-ur-Rehman., Department of Clinical Medicine & Surgery, University of Agriculture Faisalabad, Faisalabad, Pakistan | Mushtaq, Aqsa, Veterinary Research Institute, Lahore, Pakistan
The jejunum is the longest part of the small intestine and its lumen is mainly involved in the absorption of the nutrients. The present study was conducted to evaluate the effects of metronidazole, ceftriaxoine sodium and their combination on the stenotic index of the end to end jujunal anastomotic site. To accomplish this, 20 healthy stray dogs were subjected to end to end jejunal ansastmosis. Dogs in Group A (control) underwent jejunal anstomosis with no antibiotic prophylaxis, while those in Group B received surgery and metronidazole alone at 50 mg/kg, those in Group C received ceftriaxone sodium intravenously at 30 mg/kg body weight prior to surgery and dogs in Group D were given metronidazole in combination with ceftriaxone sodium at 50 mg/kg and 30 mg/kg, respectively, 2 h before surgical intervention. No significant difference (p 0.05) in the stenotic index was observed at 14 days after jejunal anastomosis. These findings indicate that prophylactic administration of metronidazole and ceftriaxone sodium alone or in combination had no significant effect on the stenotic index of the jejunum.
اظهر المزيد [+] اقل [-]Effect of repeated Paecilomyces japonica treatment on rats
2014
Kim, Y.B., Korea Institute of Toxicology, Daejeon, Republic of Korea | Hong, D.H., Chungnam, National University, Daejeon, Republic of Korea | Cho, E.S., Chungnam, National University, Daejeon, Republic of Korea | Im, W.J., Korea Institute of Toxicology, Daejeon, Republic of Korea | Kim, I.H., DAEWOONG Pharmaceutical Co., Yongin, Republic of Korea | Son, H.Y., Chungnam, National University, Daejeon, Republic of Korea
Cordyceps is a fungus used as a traditional medicine in China, Japan, and Korea. Paecilomyces (P.) japonica is a new cordyceps that was recently cultivated on silkworm pupae in Korea. The present study evaluated the toxicological effects of P. japonica in rats. Forty rats were treated with oral doses of P. japonica (0, 20, 100, or 500 mg/kg/day) for 4 weeks. Twenty additional rats were treated with 0 or 500 mg/kg/day of P. japonica for 4 weeks and then maintained for 2 weeks without treatment. Clinical signs, body weight, food and water consumption, and organ weight as well as hematology, serum biochemistry, and histopathology data were examined. Body weight gain of the group treated with 500 mg/kg/day was significantly reduced. Microscopically, karyomegaly, single cell necrosis, and mitosis were observed in the renal tubular epithelium of all treated groups. In conclusion, P. japonica caused a reduction of body weight and renal injury in rats. The no observed adverse effect level (NOAEL) of P. japonica was less than 20 mg/kg/day.
اظهر المزيد [+] اقل [-]Prevalence of virulence and cytolethal distending toxin (CDT) genes in thermophilic Campylobacter spp. from dogs and humans in Gyeongnam and Busan, Korea
2014
Cho, H.H., Animal, Plant and Fisheries Quarantine and Inspection Agency, Anyang, Republic of Korea | Kim, S.H., Viral infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea | Min, W.G., Gyeongsang National University, Jinju, Republic of Korea | Ku, B.K., Animal, Plant and Fisheries Quarantine and Inspection Agency, Anyang, Republic of Korea | Kim, Y.H., Gyeongsang National University, Jinju, Republic of Korea
The prevalence of thermophilic Campylobacter (C.) spp. in stray, breeding, and household dogs was 25.2, 12.0, and 8.8%, respectively. C. jejuni and C. upsaliensis were the predominant Campylobacter spp. from household dogs. cdtA, cdtB, and cdtC were detected by PCR in all isolates. Despite the high cytolethal distending toxin (CDT) gene prevalence, only 26 (31%) C. jejuni strains and one (15.3%) C. coli strain showed evidence of CDT production in HEp-2 cell cytotoxicity assays. Virulence-associated genes detected in the C. jejuni and C. coli isolates were cadF, dnaJ, flaA, racR, ciaB, iamA, pldA, virB11, ceuE, and docC. cadF, dnaJ, flaA, and ceuE were found in all C. jejuni and C. coli isolates. When detecting Guillain-Barre syndrome-associated genes (galE, cgtB, and wlaN), galE was identified in all isolates. However, cgtB and wlaN were more prevalent in C. jejuni isolates from humans than those from dogs. Adherence and invasion abilities of the C. jejuni and C. coli strains were tested in INT-407 cells. A considerable correlation (adjusted R©�= 0.678) existed between adherence and invasion activities of the Campylobacter spp. isolates.
اظهر المزيد [+] اقل [-]Trends in antimicrobial sales for livestock and fisheries in Korea during 2003-2012
2014
Lim, S.K., Animal and Plant Quarantine Agency, Anyang, Republic of Korea | Lee, J.E., Korea Animal Health Products Association, Seongnam, Republic of Korea | Lee, H.S., Korea Animal Health Products Association, Seongnam, Republic of Korea | Nam, H. M., Korea Animal Health Products Association, Seongnam, Republic of Korea | Moon, D.C., Animal and Plant Quarantine Agency, Anyang, Republic of Korea | Jang, G.C., Animal and Plant Quarantine Agency, Anyang, Republic of Korea | Park, Y.J., Animal and Plant Quarantine Agency, Anyang, Republic of Korea | Jung, Y.G., Animal and Plant Quarantine Agency, Anyang, Republic of Korea | Jung, S.C., Animal and Plant Quarantine Agency, Anyang, Republic of Korea | Wee, S.H., Animal and Plant Quarantine Agency, Anyang, Republic of Korea
In this study, trends in the sales of antimicrobials for use in livestock facilities and fisheries from 2003 to 2012 were investigated with regard to antimicrobial group, antimicrobial usage, and animal species. The overall amount of antimicrobials sold each year from 2003 to 2007 was 1,500 tons, after which they decreased, with the lowest sales being 936 tons in 2012. The total volume of antimicrobials used for feed additives decreased markedly by 94% from 2003 to 2012, which was mainly attributed to banning of feed additives. However, antimicrobial consumption through self prescription by farmers for disease prevention and treatment increased by 25% from 2003 to 2012. The largest volume of antimicrobials sold was for use in pigs (48~57%), followed by poultry (18~24%), fisheries (11~25%), and cattle (5~8%). Tetracycline was the highest selling antimicrobial, followed by penicillins and sulfonamides, although the overall sale of all three antimicrobials gradually decreased over the study period. This study demonstrated that the total consumption of antimicrobials has gradually decreased since 2008. Nevertheless, usage by nonprofessionals increased, which can ultimately cause emergence and spread of antimicrobial resistance. Thus, early establishment of veterinary prescription guidelines for prudent use of antimicrobials is urgently needed in Korea.
اظهر المزيد [+] اقل [-]A survey of the use of veterinary anesthetics in Korea
2014
Lee, J.W., Konkuk University, Seoul, Republic of Korea | Lee, J.I., Konkuk University, Seoul, Republic of Korea | Cho, Y.J., Seojeong College University, Yangju, Republic of Korea | Lee, Y.A., Shingu College University, Seongnam, Republic of Korea | Kim, J.I., Konkuk University, Seoul, Republic of Korea | Hwang, B.R., Konkuk University, Seoul, Republic of Korea | Kim, H.J., Konkuk University, Seoul, Republic of Korea | Jhun, H.J., Konkuk University, Seoul, Republic of Korea | Han, J.S., Konkuk University, Seoul, Republic of Korea
This study was conducted to investigate actual conditions associated with veterinary anesthetic drug use in Korea, and to obtain responses from Korean veterinarians and researchers pertaining to the use of anesthetic drugs. To accomplish this, a nationwide survey was issued to veterinarians working at animal hospitals and to researchers in the Korean Association for Laboratory Animal Science (KALAS). A self-administered questionnaire-based survey was then conducted in which respondents were asked questions about actual conditions associated with the use of animal anesthetic drugs. The survey revealed that the distribution and management of animal medicines in Korea was quite vulnerable to misuse or abuse due to a variety of factors. Therefore, a relevant regulatory system should be strictly enforced to protect vulnerable individuals from abuse or misuse.
اظهر المزيد [+] اقل [-]Bacterial strains isolated from Jeotgal (salted seafood) induce maturation and cytokine production in mouse bone marrow-derived dendritic cells
2014
Moon, S.Y., eju National University, Jeju, Republic of Korea | Park, E.J., eju National University, Jeju, Republic of Korea | Joo, H.G., eju National University, Jeju, Republic of Korea
Jeotgal (salted seafood) has been one of major fermented foods in Korea for long time. Although there are many studies about Jeotgal in various aspects of food, its immunological importance on hosts has not been elucidated yet. In this study, we investigated if several bacteria isolated from Jeotgal may modulate the function of dendritic cells (DCs), powerful antigen-presenting cells equipped with special immunological capabilities. 4 Jeotgal bacteria were selected as representatives and used for experiments. To treat viable DCs, those bacteria were killed at 60¡� for 30 min. The viability of DCs treated with Jeotgal bacteria was verified and two isolates significantly induced high production of interleukin-12, a representative cell-mediated cytokine of DCs. Surface activation and maturation markers (MHC class II, CD40, CD86) of DCs were analyzed by flow cytometer. In addition, the treated DCs showed significantly high lymphocyte stimulatory capability compared to control DCs based on allogeneic mixed lymphocyte reactions. These observations suggest that Jeotgal isolates can function as immunostimulating bacteria in hosts, like Lactobacillus. Taken together, these experimental evidences may broaden the use of Jeotgal isolates in immunological fields in addition to as a fermented food.
اظهر المزيد [+] اقل [-]Radiation safety management for diagnostic radiation generators and employees in animal hospitals in Korea
2014
An, H.J., Animal and Plant Quarantine Agency, Anyang, Republic of Korea | Kim, C.H., Animal and Plant Quarantine Agency, Anyang, Republic of Korea | Kown, Y.J., Animal and Plant Quarantine Agency, Anyang, Republic of Korea | Kim, D.H., Animal and Plant Quarantine Agency, Anyang, Republic of Korea | Wee, S.H., Animal and Plant Quarantine Agency, Anyang, Republic of Korea | Moo, J.S., Animal and Plant Quarantine Agency, Anyang, Republic of Korea
A nationwide survey on radiation safety management in Korean animal hospitals was conducted. By 2013, 53 radiation generators were registered as veterinary medical devices (41 X-ray generators and 12 computed tomography scanners). Additionally there were six approved laboratories for radiation equipment and protection facility, and five approved laboratories for radiation exposure of employees, respectively. By March 2013, 2,030 out of 3,829 animal hospitals operated radiation-generating devices. Among these devices, 389 (19.2%) out of 2,030 were not labeled with the model name and 746 (36.7%) were not labeled with production dates. Thus, most veterinary X-ray generators were outdated (42.6%) and needed replacements. When periodic inspections of 2,018 animal hospitals were performed after revision of the Veterinarians Act in 2011, the hospitals were found to be equipped with appropriate radiation generators and protection facilities. Among 2,545 employees exposed to radiation at the hospitals, 93.9% were veterinarians, 4.3% were animal nurse technicians, and 18% held other positions. Among 169 employees supervised by administrators, none of those had a weekly maximum operating load that exceeded 10mA min This study suggests that the radiation safety management system of animal hospitals was general good.
اظهر المزيد [+] اقل [-]Antimicrobial effects of natural extracts on bacteria isolated from the uterus of Hanwoo (Korean native cattle
2014
Park, B.P., Kangwon National University, Chuncheon, Republic of Kroea | Kim, K.J., Kangwon National University, Chuncheon, Republic of Kroea | Cho, Y.J., Kangwon National University, Chuncheon, Republic of Kroea | Park, S.E., Kangwon National University, Chuncheon, Republic of Kroea | Lee, J.H., Kangwon National University, Chuncheon, Republic of Kroea | Jung, B.D., Kangwon National University, Chuncheon, Republic of Kroea | Kwon, Y.S., Kangwon National University, Chuncheon, Republic of Kroea | Park, J.J., Kangwon National University, Chuncheon, Republic of Kroea | Hahn, T.W., Kangwon National University, Chuncheon, Republic of Kroea
Bacterial infection of the uterus in Hanwoo can kill embryos. Therefore, many antibiotics have been used to treat this infection in the uterus of repeat breeders. Incorrect use of antibiotics has led to resistance in bacteria. Natural compounds have used as substitutes for antibiotics because they are safe and have very mild side effects. This study was conducted to examine the antimicrobial effects of five extracts from medicinal plants including Humulus japonicas (Hj), Phelledendron amurense (Pa), Viola mandshurica (Vm), Carthamus tinctorius (Ct), and Chelidoni herba (Ch) on bacteria isolated from the uterus of Hanwoo using the paper disc diffusion method. Hj and Pa extracts had potent antimicrobial effects against Staphylococcus lentus, Streptococcus infantarius subsp. coli, and Bacillus pumilus. Pa had the greatest antimicrobial effect among the five medicinal plants and was effective against 19 types of bacteria from bovine uterus. Compared to Pa, Hj showed weaker antimicrobial effects on all the bacteria tested except Pseudomonas aeruginosa. Vm, Ct, and Ch also showed weak antimicrobial effects on the tested bacteria. The results obtained suggest that Hj and Pa are natural compounds suitable for treating bacterial infection in repeat breeders and improving conception rates of Hanwoo.
اظهر المزيد [+] اقل [-]Cerebellar encephalopathy from diminazene aceturate (beneril) toxicity in a dog
2014
Han, D.H., Kangwon National University, Chuncheon, Republic of Kroea | Yoon, W.K., Kangwon National University, Chuncheon, Republic of Kroea | Hyun, C.B., Kangwon National University, Chuncheon, Republic of Kroea
A 2-year old castrated male Alaskan malamute was referred with primary complaints of marked anemia, hemeglobinuria and depression. Laboratory tests revealed canine babesiois with severe anemia. The dog was treated by blood transfusion and beneril (diminazene aceturate, 3.5 mg/kg IM). Two days after Beneril injection, the dog suddenly showed ataxia progressing to paresis. MRI revealed irregularly diffused lesions in the cerebellum. The case was tentatively diagnosed as cerebellar encephalopathy caused by diminazene toxicity. The dog successfully recovered following steroid therapy.
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