خيارات البحث
النتائج 921 - 930 من 4,896
Associations between long-term exposure to ambient air pollution and risk of type 2 diabetes mellitus: A systematic review and meta-analysis
2019
Liu, Feifei | Chen, Gongbo | Huo, Wenqian | Wang, Chongjian | Liu, Suyang | Li, Na | Mao, Shuyuan | Hou, Yitan | Lu, Yuanan | Xiang, Hao
Previous meta-analyses on associations between air pollution (AP) and type 2 diabetes mellitus (T2DM) were mainly focused on studies conducted in high-income countries. Evidence should be updated by including more recent studies, especially those conducted in low- and middle-income countries. We therefore conducted a systematic review and meta-analysis of epidemiological studies to conclude an updated pooled effect estimates between long-term AP exposure and the prevalence and incidence of T2DM. We searched PubMed, Embase, and Web of Science to identify studies regarding associations of AP with T2DM prevalence and incidence prior to January 2019. A random-effects model was employed to analyze the overall effects. A total of 30 articles were finally included in this meta-analysis. The pooled results showed that higher levels of AP exposure were significantly associated with higher prevalence of T2DM (per 10 μg/m3 increase in concentrations of particles with aerodynamic diameter < 2.5 μm (PM2.5): odds ratio (OR) = 1.09, 95% confidence interval (95%CI): 1.05, 1.13; particles with aerodynamic diameter < 10 μm (PM10): OR = 1.12, 95%CI: 1.06, 1.19; nitrogen dioxide (NO2): OR = 1.05, 95%CI:1.03, 1.08). Besides, higher level of PM2.5 exposure was associated with higher T2DM incidence (per 10 μg/m3 increase in concentration of PM2.5: hazard ratio (HR) = 1.10, 95%CI:1.04, 1.16), while the associations between PM10, NO2 and T2DM incidence were not statistically significant. The associations between AP exposure and T2DM prevalence showed no significant difference between high-income countries and low- and middle-incomes countries. However, different associations were identified between PM2.5 exposure and T2DM prevalence in different geographic areas. No significant differences were found in associations of AP and T2DM prevalence/incidence between females and males, except for the effect of NO2 on T2DM incidence. Overall, AP exposure was positively associated with T2DM. There still remains a need for evidence from low- and middle-income countries on the relationships between AP and T2DM.
اظهر المزيد [+] اقل [-]Sewage contamination of Amazon streams crossing Manaus (Brazil) by sterol biomarkers
2019
de Melo, Moacir Guimarães | da Silva, Brina Aguiar | Costa, Gilcllys de Souza | da Silva Neto, João Cândido André | Soares, Patrícia Kaori | Val, Adalberto Luís | Chaar, Jamal da Silva | Koolen, Hector Henrique Ferreira | Bataglion, Giovana Anceski
Sewage pollution is a principal factor of decreasing water quality, although it has not been considered a real impact in Amazonia that is still considered a pristine environment around the world. Thus, this study aimed to assess the levels of sewage contamination in sediments from three streams crossing Manaus − a Brazilian city of 2,403,796 inhabitants in the heart of the Amazon rain forest. Cholesterol, cholestanol, brassicasterol, ergosterol, stigmasterol, β-sitosterol, campesterol, stigmastanol, coprostanol, and epicoprostanol levels were determined by liquid chromatography tandem mass spectrometry (LC−MS/MS). The fecal indicator, coprostanol, was found in high concentrations (509−12 830 ng g⁻¹) and high relative proportions (21–54%) in all samples collected in the Mindu stream that crosses many heavily populated districts of the city, and in the Quarenta stream that crosses the Industrial District of Manaus. The sediments of the Tarumã-Açu stream also presented coprostanol; however, concentrations (<LOQ−142 ng g⁻¹) and relative proportions (0–7%) were much lower in this stream. Sterol ratios indicate a severe contamination of the urban streams (Mindu and Quarenta) and a low to moderate contamination of the partially urban stream (Tarumã-Açu). This is the first study evaluating the levels of sewage contamination of Amazon streams using sterol biomarkers and the results obtained herein indicate the need of an immediate implementation of effective sewage treatment strategies. Additionally, these findings may be considered as baseline concentrations for future monitoring programs of that globally important environment.
اظهر المزيد [+] اقل [-]Microbial communities are sensitive indicators for freshwater sediment copper contamination
2019
Sutcliffe, B. | Hose, G.C. | Harford, A.J. | Midgley, D.J. | Greenfield, P. | Paulsen, I.T. | Chariton, A.A.
Anthropogenic activities, such as mining and agriculture, have resulted in many freshwater systems having elevated concentrations of copper. Despite the prevalence of this contamination, and the vital ecological function of prokaryotes, just three studies have investigated prokaryote community responses to copper concentration in freshwater sediments. To address this, the current study investigated these communities in outdoor mesocosms spiked with varying copper concentrations. We profiled the prokaryotic communities at the taxonomic level, using next-generation high-throughput sequencing techniques, as well as their function, using baiting with leaf analogues, and Biolog Ecoplates for community-level physiological profiling. Sediments containing just 46 mg kg⁻¹ of copper, had distinctly different microbial communities compared with controls, as determined by both DNA and RNA 16S ribosomal RNA gene (rRNA) profiling. In addition to this, sediment communities displayed a greatly reduced utilisation of carbon substrates under elevated copper, while the communities recruited onto leaf analogues were also disparate from those of control ponds. Given the vital role of prokaryotes in ecosystem processes, including carbon cycling, these changes are potentially of great ecological relevance, and are seen to occur well below the ‘low risk’ sediment quality guideline values (SQGV) used by regulatory bodies internationally.
اظهر المزيد [+] اقل [-]Modeling phosphorus sources and transport in a headwater catchment with rapid agricultural expansion
2019
Zhang, Wangshou | Pueppke, Steven G. | Li, Hengpeng | Geng, Jianwei | Diao, Yaqin | Hyndman, David W.
Increasing riverine phosphorus (P) levels in headwaters due to expanded and intensified human activities are worldwide concerns, because P is a well-known limiting nutrient for freshwater eutrophication. Here we adopt the conceptual framework of the SPAtially Referenced Regressions On Watershed attributes (SPARROW) model to describe total phosphorus (TP) sources and transport in a headwater watershed undergoing rapid agricultural expansion in the upper Taihu Lake Basin, China. Our models, which include variables for land cover, river length, runoff depth, and pond density, explain 94% of the spatio-temporal variability in TP loads. Agricultural lands contribute the largest percentage (61%) of the TP loads delivered downstream, followed by forestland (21%) and urban land (18%). Future agricultural expansion to 15% of the total basin area is possible, which could lead to a 50% increase in TP loads. According to our analysis, an average of 24% of the total P export from the watershed landscape was intercepted in ponds. The exported amount was subsequently retained by tributaries and along the mainstem river, accounting for 14% and 43% of their inflowing loads, respectively. The remaining ∼6 tons yr⁻¹ of TP was eventually transported into Tianmu Lake, in Southeastern China. The model identified several sub-catchments as hotspots of TP loss and thus logical sites for targeted management. Our study underscores the significance of agricultural expansion as a factor that can exacerbate headwater TP pollution, highlighting the importance of landscapes to buffer TP losses from sensitive hilly catchments. This also points to a need for an integrated management strategy that considers the spatial-varying P sources and associated transport of TP in precious headwater resources.
اظهر المزيد [+] اقل [-]Blueberry anthocyanin alleviate perfluorooctanoic acid-induced toxicity in planarian (Dugesia japonica) by regulating oxidative stress biomarkers, ATP contents, DNA methylation and mRNA expression
2019
Zhang, Jianyong | Wang, Bin | Zhao, Bosheng | Li, Yanqing | Zhao, Xiuyun | Yuan, Zuoqing
Blueberry anthocyanin (BA) have strong health benefits as an active natural antioxidant and perfluorooctanoic acid (PFOA) can result in oxidative stress in animals. In our study, the protective effects of BA against stress induced by PFOA was investigated in the planarian Dugesia japonica using oxidative stress biomarkers, ATP contents, ATPase activity, DNA methylation and mRNA expression. PFOA exposure could resulted in malondialdehyde production. At the same time, treatment with BA decreased the production of malondialdehyde in BA-exposed and co-treatment planarians. PFOA caused activities increase in glutathione peroxidase (GPx), glutathione S-transferase (GST) and activities decrease in glutathione reductase (GR). PFOA exposure decreased the GSH and ATP contents. Additionally, it increased the GSSG contents and ATPase activity. BA administration increased the activities of GPx, GST and GR in BA and co-treatment planarians. Meanwhile BA maintained the contents of ATP, ATPase activity, GSH and GSSG by alleviating PFOA toxicity. Moreover, PFOA and BA increased the contents of 5-methylcytosine and decreased 5-hydroxymethylcytosine in all group. In addition, PFOA and BA treated planarians significantly altered the expression of genes associated with above biochemical parameters. The results showed that the mRNA expression of gpx, Djgst, gr, Djnak and dnmt1 were significantly elevated in all groups. Alterations in the mRNA expression levels indicated a stress response to PFOA exposure and anthocyanin protection. These alterations regulated biomarkers of oxidative stress, energy metabolism and DNA methylation levels in planarians. These results indicate that BA attenuated PFOA-induced oxidative stress, energy metabolism, DNA methylation and gene expression disorders.
اظهر المزيد [+] اقل [-]Tracking the occurrence of anthropogenic magnetic particles and potentially toxic elements (PTEs) in house dust using magnetic and geochemical analyses
2019
Kelepertzis, Efstratios | Argyraki, Ariadne | Botsou, Fotini | Aidona, Elina | Szabó, Ábel | Szabó, Csaba
The influence of anthropogenic outdoor sources on the geochemical composition of house dust material in large cities is poorly understood. In this study, we investigate the magnetic signature and the concentrations of potentially toxic elements (PTEs) in randomly selected house dust samples from the metropolitan area of Athens, the most populated city in Greece. Environmental magnetic measurements, including isothermal remanent magnetization and thermomagnetism, indicated that the main magnetic mineral is coarse-grained low-coercivity magnetite. Detailed microscopic observations of the magnetically extracted material revealed the presence of three different kinds of Fe-rich particles deriving from both combustion-related and non-exhaust vehicular sources: irregularly-shaped grains and spherules of Fe-oxides, and particles consisting of metallic Fe. Further study of the morphology of single anthropogenic magnetic spherules (size > 30 μm) identified the presence of magnetite spherical particles, typically formed by industrial combustion processes. Enrichment factors (EFs) for the PTEs calculated against the Athens urban soil showed that the house dusts were very highly enriched in Cd, Cu, Zn and significantly enriched in Pb (median EF values of 34.1, 26.2, 25.4 and 10.3, respectively). The oral bioaccessibility of PTEs in the house dust, evaluated using a simulated gastric solution (0.4 M glycine), was in the order Pb > Zn > Mn > Cd > Ni > Cu > Cr > Fe. Concentrations of Pb increased with the house age. Principal component and cluster analysis demonstrated the close association of anthropogenic Cu, Pb and Zn with the magnetic susceptibility of the house dusts. We conclude that both traffic-related and industrial sources trigger the occurrence of magnetic Fe/PTEs- rich particles in house dust. These results reinforce the use of environmental magnetism determinations for assessing anthropogenic contamination of PTEs in the indoor environment in large cities.
اظهر المزيد [+] اقل [-]Impacts of cage fish farms in a large reservoir on water and sediment chemistry
2019
Varol, Memet
The Keban Reservoir, which is the second man-made waterbody in Turkey, has the biggest rainbow trout production in the country. In this study, the impacts of rainbow trout farms on water and sediment chemistry were investigated. Water and sediment samples were taken at distances of 0, 10, 25, 50 and 100 m from the edge of the cages at the three fish farms, and at the respective reference stations. Samples were also taken at 0 m stations and reference stations in the late August when there were no fish in the cages. Physico-chemical variables and trace metals were analysed in all samples. Due to likely high dilution rates and recycling processes in the water column of the reservoir, little changes in the water quality parameters associated with wastes of the fish farms were noticed. When compared with those in the sediment samples at the stations near the edge of cages, the lower concentrations of total phosphorus (TP), total nitrogen (TN), organic matter (OM), total carbon (TC), sulfide (S2−), arsenic (As), cobalt (Co), copper (Cu), manganese (Mn) and zinc (Zn), and higher values of redox potential (Eh) were found at the reference stations. According to organic enrichment classification based on S2− and Eh values, sediments of the three fish farms in the period when there were fish in the cages fell into the oxic category, whereas sediments in the August (no fish farming activity) fell into the normal category. Also, it was found in the August that most of sediment quality parameters at the 0 m stations had close values to those at the reference stations. These results revealed that a three-month period when there were no fish in the cages allows for sediments to return to reference station conditions.
اظهر المزيد [+] اقل [-]High rates of ammonium recycling in northwestern Lake Taihu and adjacent rivers: An important pathway of nutrient supply in a water column
2019
Jiang, Xingyu | Zhang, Lu | Gao, Guang | Yao, Xiaolong | Zhao, Zhonghua | Shen, Qiushi
The ammonium (NH4+) pool in the water column of eutrophic lakes is dynamic and undergoes tightly coupled production and consumption processes because of the metabolism of bacterial and algal communities, particularly in summer. However, NH4+ recycling rates along nutrient gradients at river-lake transitional zones and the extent to which NH4+ regeneration can compensate for consumption have been poorly studied. In August (flood period) and November (normal period), 2016, NH4+ regeneration rates (REGs) and potential uptake rates (Upots) were measured in northwestern Lake Taihu and adjacent rivers. Results showed that the REGs ranged from 0.09 to 3.30 μmol N L−1 h−1 and the Upots ranged from 0.20 to 4.88 μmol N L−1 h−1, with higher recycling rates occurring at the river sites. Yet, the lake sites showed significantly higher water column NH4+ demand (WCAD) than that of the adjacent river sites during both seasons (p < 0.05), probably as a result of the low REGs and the lack of exogenous nitrogen (N) inputs. The flood period showed significantly higher REG and Upot values than those of the normal period (p < 0.05), probably controlled by higher water temperature and algal biomass. This study confirms that regenerated NH4+ was more important than the ambient NH4+ for sustaining cyanobacterial blooms in northwestern Lake Taihu and indicates that the river–lake transitional zones are key areas for N control in this hypereutrophic system.
اظهر المزيد [+] اقل [-]Physical and chemical transformations of zirconium doped ceria nanoparticles in the presence of phosphate: Increasing realism in environmental fate and behaviour experiments
2019
Briffa, Sophie Marie | Lynch, Iseult | Hapiuk, Dimitri | Valsami-Jones, Eugenia
During their lifecycle, many engineered nanoparticles (ENPs) undergo significant transformations that may modify their toxicity, behaviour, and fate in the environment. Therefore, understanding the possible environmentally relevant transformations that ENPs may undergo as a result of their surroundings is becoming increasingly important. This work considers industrially produced ceria (CeO2) and focuses on a particle library consisting of seven zirconium-doped variants (Ce1-xZrxO2) where the Zr doping range is x = 0–1. The study assesses their potential transformation in the presence of environmentally relevant concentrations of phosphate. These ENPs have an important role in the operation of automotive catalysts and therefore may end up in the environment where transformations can take place. Samples were exposed to pH adjusted (c. 5.5) solutions made up of either 1 mM or 5 mM each of KH2PO4, citric acid and ascorbic acid and the transformed particles were characterised by means of DLS – size and zeta potential, UV/VIS, TEM, FT-IR, EDX and XRD. Exposure to the phosphate solutions resulted in chemical and physical changes in all ceria-containing samples to cerium phosphate (with the monazite structure). The transformations were dependent on time, ceria concentration in the particles (Ce:Zr ratio) and phosphate to ceria ratio. The presence of Zr within the doped samples did not inhibit these transformations, yet the pure end member ZrO2 ENPs showed no conversion to phosphate. The quite dramatic changes in size, structure and composition observed raise important questions regarding the relevant form of the materials to investigate in ecotoxicity tests, and for regulations based on one or more dimensions in the nanoscale.
اظهر المزيد [+] اقل [-]Research and management of plastic pollution in coastal environments of China
2019
Wang, Mary H. | He, Yaodong | Sen, Biswarup
Marine plastic waste has become an ever-increasing environmental threat in the world’s ocean largely due to their unique properties and ubiquitous occurrence. They include diverse forms of land- and ocean-based sources of plastics and are estimated to account for up to 85% of marine debris worldwide. As secondary pollutants, marine microplastic particles (<5 mm) are derived from pellet loss and degradation of macroplastics. Up to now, several reports have proposed negative impacts of both macro-sized and micro-sized plastics on marine biota. As one of the rapidly growing economies, China is the topmost contributor of plastic waste in the world. China’s massive impact on the plastic levels of the ocean are a definite cause of concern and is developing multiple economic, environmental and biological complications. The research of plastics impact on coastal environments in China is only incipient. Here we review the available information on plastic waste, their impacts on marine biota and human health, and Chinese government policies and management initiatives. Although Chinese coastal environments (surface water, coastal sediments, water column) are affected by microplastics pollution, both from land-based and sea-based activities, their impacts on marine biota remain to be elucidated. Though national-level policies are modern and well suited for minimizing the impacts of plastic pollution, there is hardly any legislation for containment of microplastic pollution. Our objective is to review and summarize the information about the occurrence, impacts, and management of plastic pollution in the Chinese coastal environments in order to comprehend their widespread repercussions.Microplastics are increasingly being detected and quantified in Chinese coastal environments and legislation for containment of such pollution is highly recommended.
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