The objective of this study was to observe and evaluate the ability of innovative vascular prosthesis, made in Riga Technical University (RTU), to incorporate in a canine model. The research has been performed in Veterinary Medicine Faculty of Latvia University of Agriculture since July 19. 2011. The research was approved by the Food and Veterinary Service of the Republic of Latvia. The research is realized within the framework of European Social Fund co-financed project ‘Establishment of interdisciplinary research groups for new functional properties of smart textiles development and integrating in innovative products’ (ESF No 2009/0198/1DP/1.1.1.2.0./09/APIA/VIAA/148). RTU produced aortic grafts 5-8 mm in diameter and 8 mm to 18 mm long were implanted retroperitoneal in 9 female, 1-3 years old Beagle dogs. Once before and regularly after the surgery, abdominal aortic and vascular graft diameter was measured in cross sections. Blood pressure was measured before and regularly after the procedure. Results show no significant differences in aortic and graft diameter before and 12 months after the operation and there are no significant differences in systolic and diastolic blood pressure before and 6 months after the aortic surgery at a significance level α 0.05. The study shows that the innovative aortic prostheses do not change in diameter and abdominal aorta transplantation surgery does not cause significant variations in blood pressure. Study is continued to find out later reactions to synthetic vascular graft.

The aim of this study was to find out the biointegration of innovative vascular prosthesis, made in Riga Technical University (RTU), in dog’s abdominal aorta. The research is being performed in Veterinary Medicine Faculty of Latvia University of Agriculture since July 19. 2011. We used 9 female gender and 1-3 years old Beagle dogs in this study. The research is approved by the Latvian Republic Food and Veterinary Service. The study is carried out in the frame of European Social Fund co-financed project ‘Establishment of interdisciplinary research groups for a new functional properties of smart textiles development and integrating in innovative products’ (ESF No. 2009/0198/1DP/1.1.1.2.0./09/APIA/VIAA/148). 5-8 mm in diameter, 8 mm - 18 mm in length RTU produced aortic grafts were implanted retroperitoneal in dogs. Before the surgery the diameter of abdominal aorta was measured in cross sections, afterwards – cranial and caudal from the prosthesis, as well cross-section diameter of vascular graft was measured. Blood pressure was measured before the surgery and after the procedure on regular basis. Results are the following: there are no significant differences in aortic and graft diameter before and 1-2 months after the operation, there are no significant differences in systolic and diastolic blood pressure before and four months after the surgery at significance level α = 0.05. The study shows that the innovative aortic prostheses don’t change in diameter, and surgery like abdominal aorta transplantation doesn’t cause significant variations in blood pressure. The study is being continued to find out later reactions to synthetic vascular graft.