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Neural and humoral influence on the regulation of gastric acid secretion in postnatal ontogenesis of the calf
2001
Ilgaza, A. (Latvia Univ. of Agriculture, Jelgava (Latvia). Faculty of Veterinary Medicine. Preclinical Inst.)
It is well known that secretion of gastric acid is regulated neurally by the stimulation of n.vagus and humorally by the activation of histamine H2 receptors in parietal cells. The purpose of the investigation was to clear up neural and humoral regulation mechanisms of gastric acid secretion in the postnatal ontogenesis of calves. Four calves from 5 to 14 weeks of age with chronical fistulae in abomasum have been investigated. Two electrode pH-probe has been used for measures. Atropine sulphate (0,06 mg kg*[-1) IV infusion) has been used to stop function of n.vagus, and cimetidine (0.16 mg kg*[-1) IV infusion) to block humoral regulation. The results clearly show that both, atropine sulphate and cimetidine, demonstrate some blocking influence on the HCL of abomasum in calves of different age.
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