Assortment improvement is a natural process of updating varieties and improving the quality of variety assortment. The article presents the results of studying the introduced grape (Vitis vinifera) varieties in the conditions of the southeast of Kazakhstan, in particular in the bottom-mountain area of Almaty region. The beginning and the end of the main phenological phases passing for the vegetative period in a grape plant directly depended on climatic and weather conditions of this district. It is established that varieties ‘Kuibyshevsk early-maturing’, ‘Iyulsky’ and ‘Priusadebny’ have a good degree of eyes wintering buds and are able to give a yield of high quality in this area in comparison with recognized variety ‘Almaty early-maturing’.

The article discusses the results of comprehensive studies histomorphological signs of skin and hair of sheep (Degeress) of various stripes, especially the thickness of the skin and its layers that are commonly identified indicators. Studies allow to bring the scientific basis for the proper development of activities aimed at increasing production of wool, quantity and quality of which skin microstructure largely depends on. Sheep of different colors have a specific feature on the histological structure of the skin, which is essential for the development of effective methods of selection that enhance productivity of sheep wool. The researches have established that brown suit sheep has thickened skin as compared to red and gray color (p is less than 0.01). In turn, pilar layer of the skin is also much thicker at brown coloration sheep (2029.7 ×10E-6 m) than in sheep red (1850.6×10E-6 m) and sulfur (1773.7×10E-6 m) suits, the difference is statistically highly significant (p is less than 0.001). The thickness of the pilar layer is up to 70% of the dermis, which varies depending on sheep lear ranging from 1773.7×10E-6 m to 2029.7×10E-6 m. Reticular layer thickness varies depending on sheep lear ranging from 743.5×10E-6 m to 826.4×10E-6 m.

This article presents the results of studies of the chemical composition of the fish meat while using as a feed additive zeolite of Chankanay origin. The research was conducted during 2011-2013 at the Department of Veterinary-sanitary examination and hygiene of the Kazakh National Agrarian University and at the laboratory of JSC ‘Kazakh Academy of Nutrition’ LTD ‘NUTRITEST’. The material of study was the zeolitic tuff of Chankanay deposit (Almaty region) and two-year trout Oncorhynchus mykiss. For the research we used feed by recipes of GosNIORH - 12-80. The chemical composition of fish meat was determined by a set of methods: moisture by drying at 105 °C, fats by Soxhlet, total protein by modified Kjeldahl method (ISO 937:1974), and minerals by incineration in a muffle furnace. Calorie content of meat was determined by Alexandrov’s formula: X = C - (F+A) ´ 4.1 + F ´ 9.3. Fatty acid composition of fish meat was determined by gas-liquid chromatography. Thus, the results are the indirect evidence that zeolites added to primary diet for growing fish, do not adversely impact proteolytic enzyme systems of fish, that is, have no negative effect on fish organism.

This article presents data on veterinary and sanitary evaluation of cows’ (Bovis) meat infected by leptospirosis. The material for the study was a sample of muscle tissue of m. longissimus dorsi taken at slaughter of 10 cows (Bovis) kept on farms in Almaty region. The following parameters have been examined in muscle tissue: water, protein, fat, ash, amino acid composition. Besides the biochemical studies we also measured pH of meat, put the reaction of neutral formalin (Formalin test) and determined the biological value of meat. It was determined that physical and chemical characteristics of sick animal meat have significant deviations from the norm. Such meat rapidly accumulates products of protein decay. The amount of essential and nonessential amino acids decreases, which indicates low nutritional value of meat. Meat of cattle infected by leptospirosis concedes by nutritional and biological value comparing to meat of healthy animals.

Avian metapneumovirus (AMPV), formerly known as avian pneumovirus (APV) is epizootic agent of turkey rhinotracheitis (TRT) and swollen head syndrome (SHS) in turkeys and chickens. The infection primarily affects the upper respiratory tract of young birds (broilers), while also decreases egg production of adult hens. Thus, the development of infection in susceptible birds of any age can cause serious economic losses. The purpose of this study is to test serums from broilers and hens for the presence of antibodies against the avian metapneumovirus. In this series of studies 317 serum samples taken from one 1 day to 75 weeks old birds were tested. Thus, on the basis of serological tests of blood serum and of chicken flocks and broilers, we had a preliminary diagnosis on the presence of avian metapneumovirus infection. Serological studies of unvaccinated against avian metapneumovirus infection bird flocks using the ELISA method showed antibody titers on average at 22 859 ± 4133. Avian metapneumovirus infection in birds was accompanied by a decrease in egg production of chicken flocks by 8.0 - 12.8%.

This article summarizes data of determining a therapeutic dose of a new immunocorrecting drug, dermatocytoglobulin, developed by the authors of this study. It has been established that this drug has a therapeutic immunocorrecting effect on allergic dermatitis. Subjects of the study cattle, horses, of Raimbek – Commercial Diary Farm, 56 dogs and 35 cats admitted to a veterinary clinic. It has been established that administration of dermatocytoglobulin in trial groups reduces autoantibody titers until their elimination on the 12th day, dose of 0.2 cm3 per 10 kg while autoantibody titers in control groups were identified on the 30th day.

The concepts of bioeconomy development require the integration of different sectors and economic activities. Bioeconomy helps to achieve the goals of sustainable development. This paper provides an overview of the cooperation for the need of bioeconomy development, examining it from agricultural cooperatives development, theoretical concept and European countries policy and Kazakhstan perspective. The research methods are induction and deduction, monographic, the group interview, statistical data analysis and synthesis, descriptive, matching and comparison and other methods. The cooperation passes through several levels of development – information, consultation, joint action, collective decision-making. The cooperation within farmers (horizontal cooperation) is so far narrow and limited to traditional cooperatives that bring together producers of the same product. New forms of cooperation and more diverse directions in national, regional and local levels are needed to develop the bioeconomy. Partnerships, the interdepartmental and interdisciplinary cooperation based on knowledge and innovation should be established between farmers, agri-food companies and scientific institutions, Kazakhstan and other countries universities. The agricultural and rural development advisory system should be improved, and new measures to promote communication, counselling and cooperation should be introduced.

This paper summarizes the results of a theoretical study as well as practically oriented research about the concept of managing the social sphere of the village and considers the problem-perspective field of development the social infrastructure management in the villages of the Republic of Kazakhstan. The chosen topic is relevant as an insufficiently studied scientific problem, and also has practical significance for the well-being and stable development of rural areas. The study describes the scheme of management of the rural social infrastructure in the Republic of Kazakhstan from the standpoint of object-subject, methods and results. Interviews of the rural population were conducted about the satisfaction with the rural social infrastructure and attitude towards the work of local governance. Rural settlements of Mangystau oblast currently have an average not significant level of social infrastructure development and the level of satisfaction of residents in different areas with its condition varies from very low to sufficient. The most important principles for the development of definition of rural social infrastructure management and its functions have been highlighted with the help of a comparative analysis of various approaches. According to the results of the study, it was concluded that the development of promising directions of management the rural social infrastructure requires a comprehensive study and evaluation of the facilities, mechanism and principles of this management and the identification of its current problems with regional development tasks.

The aim of the present study was to analyse and compare camel milk powder quality and functional properties produced with spray-drying and freeze-drying techniques. Freeze-drying is recognized as an advanced method for the production of high-quality dried products, but it has been a costly process for production of camel milk powder. Spray-drying and freeze-drying of camel’s milk demonstrated that the nutritional characteristics of this product basically remained unchanged compared to fresh milk. The differences were found analysing flowability, solubility and hygroscopicity of camel milk powder samples obtained with freeze-drying and spray-drying technique. Analysed quality indices of camel milk demonstrated that spray-drying has lower impact on camel milk powder physical properties in comparison with freeze-drying.

This article describes the results of a pre-clinical study of immunogenicity and effectiveness of an inactivated pandemic vaccine (Refluvac®) on model mice. Mice received two 0.5 ml intraperitoneal inoculations with an interval of 14 days in three doses: containing 10.0, 5.0 and 2.5 μg HA (hemagglutinin) per animal. As a comparator preparation, the study used a semi-finished product (SP) vaccine diluted with phosphate buffered saline (PBS) to obtain HA concentrations of 5 μg and 10 μg. For a control group, the study used PBS as the negative control. We determined the vaccine’s protective effectiveness level by analysing its response in animals challenged with a pandemic А/California/7/09 (Н1N1) pdm09 virus. We assessed the immunogenicity of the vaccine by examining the mean geometric titre (GMT) of antibodies against the influenza virus as measured by hemagglutination-inhibition test (HAI). In the course of testing the GMT, we noted a dependence of the concentration of antibodies in serum on the vaccine’s antigen load. The highest GMT was observed in the group of mice vaccinated with a HA load of 10.0 μg – it amounted to 278.6 (95% CI, 135.6 to 572.4). We established a high tolerability of the vaccine tested. Our study shows that Refluvac® yields a high degree of protectivity against influenza A/H1N1 and prevents clinical signs, death or accumulation of influenza virus in the organs of vaccinated animals. There were deaths and clinical signs including general depression, hypodynamia and anorexia in the negative control group. The results of our study were used for the clinical study of the first Kazakhstan produced Refluvac® vaccine against pandemic A/H1N1 influenza virus.