The diamondback moth (DBM), Plutella xylostella (Linnaeus, 1758) (Lepidoptera: Plutellidae), is a severe and most destructive pest of cruciferous vegetables in many parts of the world, including Nepal. The natural history and ecology of the diamondback moth are summarized here, along with appropriate management options. Caterpillar is the most devastating stage of DBM that matures and causes “windowing” damage, leaving only the epidermis. Biological control, cultural practices, effective chemical control, botanical pesticides, and host plant resistance are the most viable options. Insecticide abuse and resistance concerns are likely to persist, as numerous research-based outcomes have proven that none of these measures will suffice independently. However, these techniques can complement each other and result in a better long-term management system when combined. This review highlights the integrated eco-friendly management strategies for DBM and other cruciferous insect pests. Integrated Pest Management (IPM), which focuses on sustainable production, has shown promising results. Modern management techniques include genetic modification, use of parasitoids, modified cultural methods, the precautionary application of chemicals, resistant cultivars, fungal, bacterial (Bt. based biopesticides), and viral entomopathogens, etc., which are found to be more effective and eco-friendlier.