Much of the sustained agricultural growth necessary for poverty reduction and sustainable development comes from adequate and expanded improved agricultural inputs use like hybrid seeds, pesticides, insecticides, herbicides, fungicides, and inorganic fertilizer. However, smallholder farmers faced various and empirically unidentified constraints in the sustainable use of improved agricultural inputs. This study, therefore, is to examine the trends and challenges farmers faced to use improved inputs. The study has used secondary data from various databases such as FAOSTAT, World Bank, Ethiopian Institute of Agricultural Research and agricultural statistics. Simple graphical sketch, tabular and percentage analysis was employed for interpretation of the data. The study revealed that the trends in the use of various improved inputs are not based on the regular basis. The sustainable improved input intensification by smallholder farmers was influenced by various socio-economic, physical, and institutional factors. Understanding trends and challenges in input utilization provide baseline information for input intensification policies and strategies. Therefore, this review pointed out that it is possible to increase inputs intensification by smallholder farmers.