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النتائج 181 - 183 من 183
Landscape Design in Hospital Gardens: The Example of Selcuk University Medical Faculty Hospital
2023
Ruhugül Özge Gemici
Hospital gardens, located within urban open-green areas, are places created for patients coming to the hospital, their relatives and the staff working in the hospital to spend time in an environment where they can renew themselves. The importance of these places is increasing day by day. The purpose of this study is to examine the landscape design of the Selcuk University Faculty of Medicine hospital garden located on the Selcuk University Alaeddin Keykubad Campus. The findings show that the hospital garden was generally not designed in accordance with landscape design principles. With the suggestions developed, this hospital garden can be redesigned in accordance with landscape design principles and made more comfortable for people using the hospital garden.
اظهر المزيد [+] اقل [-]Investigation of Selcuk University Alaeddin Keykubat Campus in Terms of Xeriscape Design
2023
Ruhugül Özge Gemici
Drought and thirst are among the most important problems in today's world where water resources are depleted more rapidly due to global warming and climate change. The use of plant species with high water needs in landscaping causes an increase in the need for irrigation and more water consumption. For this reason, the need for xeriscape design in landscape areas has increased in recent years. The aim of this study is to examine and evaluate the xeriscape landscaping in Selcuk University Alaeddin Keykubat Campus in line with the xeriscape principles. As a result of the examinations, it was determined that the xeriscape design areas in the campus were generally created in accordance with xeriscape principles.
اظهر المزيد [+] اقل [-]The Relationship Between Vitamin B12 and Telomere Length: A Systematic Review
2023
Zeyneb Yıldırım | Emine Merve Ekici
Telomeres are natural nucleoprotein structures that cover the ends of chromosomes. The phenomenon of telomere shortening, which plays a crucial role in maintaining the stability of the genome, occurs gradually over time when cells undergo division due to the end replication issue. Multiple studies have demonstrated a correlation between telomere shortening and a range of illnesses, including diabetes, dyslipidemia, cardiovascular disease, cancer, and mortality. Diet and lifestyle can affect telomere length. There exists a beneficial association between telomere length and the Mediterranean diet, particularly with regards to the consumption of dietary fiber derived from whole grains and vegetables. Micronutrients such as vitamins and trace elements also play a role in cell metabolism. Some micronutrients, such as vitamin D, folate, and vitamin B12, are associated with telomere biology and cellular aging. Vitamin B12 is essential for DNA synthesis and epigenetic methylation processes. The present systematic review examines the results from clinical trials conducted in humans evaluating the role of vitamin B12 on telomere length. Cellular senescence is a state characterized by inflammation, altered cellular metabolism, genomic instability, and telomere dysfunction, which can be induced by changes in methylation patterns and oxidative stress. Vitamin B12 maintains antioxidative defense. Through these pathways, sufficient amounts of vitamin B12 may potentially play a role in the restoration of DNA damage. Most of the evidence is based on very few randomized clinical trials. Therefore, more extensive prospective cohort studies and better-designed randomized clinical trials are required to validate the correlations outlined in this review.
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