In this study, the eggs produced in uncontrolled village conditions were compared to free-range, organic and cage-system in two seasons, in autumn and spring, in terms of external and internal quality traits. In the autumn and spring period, 110 eggs were collected from the village eggs and 50 eggs from other production systems. In order to determine the fertility in the village eggs, 60 eggs were placed in a laboratory type incubator in both seasons and fertility control was made at the 18th day. All data of egg quality traits were performed by taking the average of the two seasons. Egg shape index, shell ratio, shell thickness, shell cleanness, shell defects, albumen and yolk traits differed significantly among production systems (P < 0.05). The lowest shape index, shell thickness and shell cleanness were found in village eggs. Higher shell rates were determined from eggs in cage and organic production compared to others (P < 0.05). The yolk height and yolk index were the lowest and the yolk colors were the darkest in the white cage eggs (P < 0.05). Brown cage eggs showed the better results in the majority of their quality traits. However, they had a higher meat and blood-spot level than other systems. In addition, the presence of cockerels in the village flocks caused the fertile eggs and approximately 85% fertility was obtained. Our results showed that it has become obvious that the village hen and free range hen eggs which can be marketed in high prices compared to the commercial eggs, have no superiority in terms of the traits they are considered. Besides, as they are significantly fertile, especially in hot summer months, according to storage duration and conditions, the probability of embryo development for these eggs has turned to be of high importance for consumption.

Bağışıklık sistemi vücudu hastalık yapıcı patojenlere karşı koruyan temel savunma sistemidir. Bu savunma sistemi farklı mekanizmalarla etkili olmaktadır. Bağışıklık sistemi, antijen adı verilen vücudun kalıtsal yapısına yabancı olan her türlü yapıya karşı etki gösterir. Vücuda dışarıdan gelen hastalık etkenleri öncelikle doğal bariyerlerle karşılaşmaktadır. Doğal bariyerleri aşmayı başaran etkenler kemik iliği, timus, lenf bezleri ve dalak gibi özelleşmiş organlarda üretilen savunma hücreleri ile karşılaşır. İlk aşamada makrofajlar ve fagositler devreye girer daha sonraki aşamada ise B ve T lenfositleri sürece dahil olurlar. B lenfositlerinden salgılanan antikorlar bağışık sisteminin en önemli savunma mekanizmalarından birini oluşturmaktadır. Antikor moleküllerinin vücudun savunmasındaki bu önemi bilim insanlarını bu alanda çalışmaya yöneltmiştir. Bu doğrultuda 1975 yılında Georges Köhler ve Cesar Milstein, koyun alyuvarları ile immunize ettikleri farelerin B lenfositleri ile fare myeloma hücrelerini birleştirerek oluşturdukları hibrit hücreler ile yeni bir tedavi stratejisinin kapısını açmışlardır. Bu hibrit hücreler sadece istenen antijene bağlanan monoklonal antikor sentezleyebilme yeteneğine sahiptir. Monoklonal antikorlar tıp dünyasında hastalıkların teşhisi, tedavisi ve biyokimyasal analizler gibi birçok alanda kullanmaktadır. Günümüzde hala monoklonal antikora dayalı tedavi ve tedavi seçenekleri üzerinde çalışmalar devam etmektedir. Bu derlemede monoklonal antikorlar ve tedavide kullanımı üzerine genel bilgiler verilecektir.

Urban green spaces are areas established to meet the recreational needs of urban people. Although green spaces vary from country to country and region in terms of plan and design features, they were basically created to allow people to meet with nature. Parks are the basic components of urban landscapes that provide environmental and social functional value. Urban parks, in particular, provide spaces for outdoor physical activities. In order to take advantage of the opportunities of activities in the parks, users must have convenient access to these resources. One of the most important aspects for researching the use and potential benefits of urban green spaces is the assessment of their geographic accessibility. The widespread use of smart city systems and the gradual expansion of their usage areas increase the importance of spatial analysis. Spatial analyses are used in today’s urban management in the processes of determining social needs, identifying current problems, and putting forward solutions. When spatial analyses are used together with GIS, the field of application develops even more, and it supports local governments in responding to the changing demands of the society for a better life. In the study, the adequacy and accessibility of 160 city parks in Konyaaltı District of Antalya Province were examined. In terms of the adequacy of the parks, the area value of 10 m2 per person determined with the Construction Plan numbered 3194 was taken as basis. In terms of accessibility, distance values of 200, 400, 800, 1,200 meters were examined. Neighborhood boundaries and population information were obtained from the relevant units, and Arc-GIS software was used in the analysis. It was determined that the parks in Konyaaltı district were insufficient in terms of adequacy and accessibility. Finally, suggestions were made in terms of increasing the adequacy of the parks and ensuring accessibility.

The sculpture, which is the expression of beliefs and fears in prehistoric times, has taken on different roles as an urban reinforcement element in all cultures with numerous themes. In the Middle Ages, it became an organic part of the architectural structure, teaching the truth about religious beliefs. With the Renaissance movement, it became independent by breaking away from the architectural structure and moved to the urban space. In the twenty-first century, its dimensions have grown to be equivalent to architecture, it has created its own space and established new aesthetic and functional relations with the audience. In this study, the relationship of some sculptures on the Alaeddin Keykubat campus of Selcuk University with the landscape elements was examined in terms of design elements and basic design principles. In the light of the data obtained, suggestions have been developed in order to increase the life and aesthetic quality of the campus.

Ülkemizde tescili yapılmış 97 adet yerli zeytin çeşidi mevcut olup, Saurani de Hatay/Altınözü orijinli zeytin çeşididir. Akdeniz Bölgesi zeytin üretiminde birinci sırada olan Hatay ili zeytin yetiştiriciliği için oldukça uygun iklim ve toprak koşullarına sahiptir. Bu çalışmanın amacı Hatay’da yetiştirilen Saurani zeytin çeşidinden elde edilen yağın serbest yağ asitleri, peroksit sayısı ve yağ asitleri kompozisyonu gibi kalite parametreleri üzerinde zeytin olgunluğunun etkisinin araştırılmasıdır. Bu amaçla 2020 üretim sezonunun 3 farklı olgunluk döneminde Saurani çeşidinden toplanan zeytinlerden mekanik yöntemle zeytinyağı elde edilmiştir. Saurani zeytinyağında serbest yağ asitleri %0.62-0.91 (oleik asit), peroksit sayısı 3.68-5.26 meq O2/kg olarak belirlenmiştir. Olgunlukla birlikte serbest yağ asitleri miktarı artmıştır. Saurani zeytinyağında oleik asit %66.32-68.79, palmitik asit %12.47-13.75, linoleik asit %11.43-13.84, stearik asit %3.16-3.42, palmitoleik asit %1.12-1.34, linolenik asit %0.88-1.01 ve araşidik asit %0.41-0.52 aralıklarında belirlenmiştir. Olgunlukla birlikte oleik asit içeriğinde azalma, linoleik asit içeriğinde ise artış kaydedilmiştir. Saurani zeytinyağının incelenen özellikler bakımından Türk Gıda Kodeksi Zeytinyağı ve Pirina Zeytinyağı Tebliği’nde (2017) belirtilen sınırlar içerisinde olduğu belirlenmiştir.

In the present study, totally 49 samples, which showed the symptoms of leaf and shoot blight and cankers with brown discoloration of necrotic tissues on mature branches, were collected from 22 districts and areas of Konya Province between 2017 and 2019. Presence rate of E. amylovora in collected samples, showing symptoms of the disease, from the province was determined to be 40% for blackberry and raspberry and 33% rosehip for rosehip in three years. Bacteria consistently isolated from the diseased tissues were identified on the basis of biochemical, physiological, and molecular tests, comparing with a reference strain of E. amylovora, isolated from blackberry (Kbb 371). Twenty seven representative bacterial strains were gram-negative, rod-shaped, mucoid, fermentative, positive for levan formation and acetoin production, no growth at 36°C, positive for gelatin hydrolysis, and negative for esculin hydrolysis, indole, urease, catalase, oxidase, arginine dehydrolase, reduction of nitrate, acid production from lactose, and inositol. All strains induced a hypersensitive response in tobacco (Nicotiana tobacum cv. White Burley) 24 h after inoculation with a 108 CFU ml-1 bacterial suspension in sterile distilled water. The strains were identified as E. amylovora using the species-specific primers set A/B (1), which amplified a 1-kb DNA fragment in PCR, and the matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) method. In order to fulfill the Koch postulates, pathogenicity test was confirmed by injecting bacterial suspensions of 108 CFU ml-1 in sterile distilled water into the shoot tips of 3-year-old blackberry R. fruticosus cv. Chester, raspberry R. idaeus cv. Heritage and rosehip R. canina. All tests were repeated three times. The bacterium was re-isolated from inoculated plants and identified as E. amylovora. Phytosanitary measures are needed to prevent any further spread of the bacterium as potential inoculum sources to new blackberry, raspberry and rosehip growing areas.

Çalışma, endofit bakteri uygulamalarının farklı kuraklık stresi altında yetiştirilen biber fidelerinin gelişimi üzerine etkisini ortaya koyabilmek amacıyla, kontrollü koşullarda saksı denemesi şeklinde yürütülmüştür. Biber çeşidi olarak Mostar F1; endofit bakteri olarak da Ochrobactrum sp. (CB36/1) ve Bacillus sp. (CA41/1)) izolatları uygulanmıştır. Bakteri uygulaması, 109 cfu/ml yoğunluğunda iki kez (ilk uygulama 10 ml- ikinci uygulama 15 ml) yapılmıştır. Tohum ekiminden itibaren, 52 gün boyunca tüm saksılar düzenli olarak sulanmıştır. Kontrol (B0) uygulamalarında sulamalara 2 gün aralıklar ile devam edilmiş; ikinci uygulamada (B1) dört günlük bir kuraklık stresi ve son uygulamada (B2) ise 8 günlük bir kuraklık stresi uygulanmıştır. Bitki gelişim parametreleri olarak; gövde çapı, sürgün boyu ve kök uzunluğu, sürgün yaş ve sürgün kuru ağırlığı, yaprak sayısı, kök yaş ve kök kuru ağırlığı incelenmiştir. B1 ve B2 stres uygulamalarının, bitki gelişimine etkisinin genel olarak olumsuz olduğu tespit edilmiştir. Endofit bakterileri uygulamalarının ise farklı kuraklık streslerinin yol açtığı olumsuzluğa karşı nispeten olumlu düzeyde etkilere sahip olduğu belirlenmiştir.

Softening of cheese surface is a common problem especially in brined cheeses. In this study, the effects of the brine calcium concentrations on the texture of fresh perline Mozzarella cheese were investigated. The compositions of cheeses were analyzed 2 weeks after production. Brine protein content were monitored at 2 and 4 week of storage. The effect of the brine calcium concentration on the texture and meltability of cheeses were monitored Texture Profile Analysis (TPA) and Schreiber meltability test at 2 and 4 weeks of storage. The decrease in brine calcium concentration increased the protein transfer from cheese to brine, leading to an increase in the moisture content of cheese. As the calcium concentration increased in brine, an increase in the hardness, and decrease in adhesiveness and meltability of the cheeses were observed during storage. In conclusion, softening/solubilization of the surface of fresh perline Mozzarella cheese can be prevented with increasing the brine calcium concentration.

Potato (Solanum tuberosum L.) is one of the most significant vegetable crops for humans along with corn, wheat, and rice. In this study, quantitative analysis of phenolic compounds was carried out for 21 promising potato clones and three commercial cultivars. LC–MS/MS was used for the chemical analyses. The TOGU 3/518 clone had the highest level of 4-hydroxybenzoic acid as 138.51 ± 7.35 µg/kg. TOGU 12/29 and TOGU 2/198 clones, on the other hand, had 126.24 ± 2.29 and 125.29 ± 2.74 µg/kg of 4-hydroxybenzoic acid, respectively. Salicylic acid which is a pharmaceutically significant compound was found in TOGU 3/518 clone (125.66 ± 11.51 µg/kg) as a major product. This compound was also found in TOGU 2/198 (111.27 ±1.31 µg/kg) and TOGU 12/29 clones (111.07 ± 3.68 µg/kg) as the third and fourth most abundant. In terms of caffeic acid, TOGU 3/110 clone contained the highest level (42.50 ± 3.73 µg/kg). While TOGU 7/146 clone included the most protocatechuic acid (53.98 ± 1.47 µg/kg), TOGU 3/480 clone consisted of most gentisic acid (30.79 ± 0.51 µg/kg). Quercetin, an important flavonoid found many aromatic and medicinal plants, was highest in TOGU 12/29 clone (6.27 ± 0.15 µg/kg).

Throughout the world, Pharmaceutical sector is an instant component in health-care systems. It involved in invention, improvement, propagation, and trading of medicines for human health and animal health. Scientific investigation is the base of pharmaceutical industries which helps to improve of new formulation of various drugs that used to treatment of different diseases and confusions. Proper personal hygiene is mandatory in pharmaceutical sector which will be helpful to control the quality of the products and minimize various types of filth that effects virtue of medicinal product. In pharmaceutical industry hygienic and safety measures are deliberated two utmost significant sights. To ensure the safety of workers, it is compulsory to fix practices of hygienic management and monitoring filth inside the biological and pharma laboratory as well as industry. This study will help to set an occupational health of the researchers, workers in laboratory by making intimation about the bad effects of personal hygiene and less protective management.