New Route to 3-Alkylthiazolo[3,2-a]benzimidazole Derivatives
2005
Christian Roussel | Federico Andreoli | Mihaela Roman | Maria Hristova | Nicolas Vanthuyne
3-Alkyl-thiazolo[3,2-a]benzimidazole derivatives are obtained in high yieldsvia the corresponding 4-alkyl-N-3-(2-aminophenyl)-thiazoline-2-thiones which are easilyprepared from 1,2-diaminobenzene, CS2 and halogenoketones. This new route comparesadvantageously with the classical mercaptobenzimidazole routes in term of simplicity,isolated yields and availability of the starting materials.
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