Liver Transcriptome Profiling Identifies Key Genes Related to Lipid Metabolism in Yili Geese
2023
Huajiao Dong | Jie Zhang | Yingying Li | Hafiz Ishfaq Ahmad | Tiantian Li | Qianqian Liang | Yan Li | Min Yang | Jilong Han
The Yili goose is the only indigenous goose breed that originates from Anser anser in China, known for its adaptability, strong flying ability, and tender meat with a low body lipid content. The liver plays a crucial role in lipid and glucose metabolism, including the intake, secretion, transportation, and storage of fatty acids (FAs). In this study, RNA-sequencing (RNA-seq) technology was performed to analyze the liver differentially expressed genes of Yili geese and their hybrid geese to investigate differences in liver lipid and glucose metabolism. A total of 452 differentially expressed genes (Q-value <: 0.05) were identified. Notably, in KEGG enrichment analysis, four pathways (Q-value <: 0.05) were enriched to be associated with lipid and glucose metabolism, including the metabolic pathway, PI3K&ndash:Akt signaling pathway, glycolysis/gluconeogenesis, and steroid biosynthesis. This study provides insights into potential candidate genes and metabolic pathways that affect the liver lipid metabolism of Yili goose. These findings provide a better understanding of animal liver lipid deposition and metabolism.
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