Mutagenicity and clastogenicity potential of five Philippine medicinal plants
1988
Sylianco, C.Y.L. | Basilio, B. | Mendoza, L.C.V. | Ang, D. | Villena, M.C. | del Rosario, S. (Philippines Univ., Diliman, Quezon City (Philippines). Dept. of Chemistry)
Expressions from rhizomes of Acorus calamus Linn., decoctions from leaves of Cassia tora Linn., seeds of Glycine max (Linn.) Merr., tubers of Kaempferia galanga Linn. and roots of Vetiveria zizanioides Stapf. were studied for mutagenicity and clastogenicity potential using Rec assay, Ames test, host-mediated assay and micronucleus test. The plant test systems did not possess direct DNA damaging capacity. These were not mutagenic before and after metabolic activation. No chromosome breaking effects were observed.
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