Melanopsin (Opn4) is an oncogene in cutaneous melanoma
2022
Leonardo Vinícius Monteiro de Assis | José Thalles Lacerda | Maria Nathália Moraes | Omar Alberto Domínguez-Amorocho | Gabriela Sarti Kinker | Davi Mendes | Matheus Molina Silva | Carlos Frederico Martins Menck | Niels Olsen Saraiva Câmara | Ana Maria de Lauro Castrucci
Melanopsin (Opn4) is identified as an oncogene in cutaneous melanoma, with the loss of Opn4 found to be associated with reduced proliferation and tumor growth, due to changes in immune responses and Mitf signaling in vitro and in vivo.
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