Identification of TCR repertoires in functionally competent cytotoxic T cells cross-reactive to SARS-CoV-2
2021
Kanako Shimizu | Tomonori Iyoda | An Sanpei | Hiroshi Nakazato | Masahiro Okada | Shogo Ueda | Miyuki Kato-Murayama | Kazutaka Murayama | Mikako Shirouzu | Naoko Harada | Michihiro Hidaka | Shin-ichiro Fujii
Kanako Shimizu et al. identify HLA-A24 high-binding epitopes in the SARS-CoV-2 spike region and investigate their cross-reactivity with CD8+ T cell receptors. These results provide further insight into CD8+ T cell cross-reactivity toward SARS-CoV-2 and may be useful in future strategies for vaccine development.
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