An oxidative metabolic pathway of 4-deoxy-L-erythro-5-hexoseulose uronic acid (DEHU) from alginate in an alginate-assimilating bacterium
2021
Ryuji Nishiyama | Takao Ojima | Yuki Ohnishi | Yasuhiro Kumaki | Tomoyasu Aizawa | Akira Inoue
Nishiyama et al. report the biochemical pathway for the conversion of DEHU to α-ketoglutarate in the alginate-assimilating marine bacterium Flavobacterium sp. strain UMI-01. They show that a parallel oxidative pathway besides the reductive route is possible, and provide evidence that this pathway might be conserved in other alginate-degrading bacteria.
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