Extra-hematopoietic immunomodulatory role of the guanine-exchange factor DOCK2
2022
Cornelia Scharler | Rodolphe Poupardin | Patricia Ebner-Peking | Martin Wolf | Christina Schreck | Gabriele Brachtl | Andre Cronemberger Andrade | Linda Krisch | Laurence Daheron | Katharina Schallmoser | Karsten Jürchott | Judit Küchler | Harald Stachelscheid | Hans-Dieter Volk | Robert A. J. Oostendorp | Dirk Strunk
The guanine exchange factor DOCK2 regulates the development of immunomodulatory function in human stromal cells (mesenchymal stem/progenitor cells (MSPC) and fibroblasts), as demonstrated in three models.
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