Effect of Body Mass Index on the Outcome of In-vitro Fertilization/Intracytoplasmic Sperm Injection
2021
Zoofishan Imran | Haroon Latif Khan | Rabia Nafees | Humaira Humayun | Rameen Nisar
<p>Background and Objective: Obesity is becoming a global issue related to many health problems, and infertility is one of them. It has been established in literature that obesity or increased body mass index (BMI) harms the ability of a woman to conceive. Assisted reproductive techniques e.g., in-vitro fertilization (IVF) and Intracytoplasmic Sperm Injection (ICSI) are helping infertile women to conceive. This study's objective was to analyze the effect of BMI on IVF/ICSI treatment outcomes in infertile women.</p> <p>Methods: This was a retrospective cross-sectional study. Samples of 500 patients aged less than 40 years were selected at a tertiary care infertility center: Lahore Institute of Fertility and Endocrinology, Hameed Latif Hospital. The sample was collected from January 2019 to June 2019. A structured proforma was used to collect information about selected anthropometric measurements and ultrasonography findings from the files and follow-ups of the selected patients. Data was processed and analyzed in Statistical Package for Social Sciences (SPSS) version 20.0.</p> <p>Results: The age of the subjects ranged from 18 to 39 years, with a maximum number of subjects in the age category 31 to 35 years. BMI was significantly associated with number of follicles retrieved and clinical pregnancy rate (P= 0.001).</p> <p>Conclusion: Normal BMI has positive impact both on follicular response in controlled ovarian stimulation (COS) and clinical pregnancy rates in women undergoing IVF/ICSI treatment.</p>
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