Detection of additive and dominance effects of QTLs in interval mapping of F2 RFLP data
1994
Hayashi, T. | Ukai, Y. (Tokyo Univ. (Japan). Faculty of Agriculture. Dept. of Agrobiology)
A model for interval mapping of quantitative trait loci (QTLs) in an F2 population using genetic markers such as restriction fragment length polymorphisms (RFLPs) is proposed. Based on this model the log-likelihood ratio statistic is divided into two useful statistics which can be used to detect additive and dominance effects of QTLs, separately. The properties of the two statistics were investigated for the theoretical construction of critical regions to test the gene action of QTLs. The model was applied to 1000 simulated-sets of 200 F2 individuals.
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