XVth QTLMAS: simulated dataset
2012
Elsen , Jean Michel(auteur de correspondance) (INRA , Auzeville (France). UR 0631 Station d'Amélioration Génétique des Animaux) | Tesseydre , Simon (Institut National de la Recherche Agronomique, CASTANET-TOLOSAN(France). UR631 SAGA Station d'Amélioration Génétique des Animaux) | Filangi , Olivier (INRA , Saint Gilles (France). UMR 1348 Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage ) | Le Roy , Pascale (INRA , Saint Gilles (France). UMR 1348 Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage ) | Demeure , Olivier (INRA , Saint Gilles (France). UMR 1348 Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage )
Background: Our aim was to simulate the data for the QTLMAS2011 workshop following a pig-type familystructure under an oligogenic model, each QTL being specific. Results: The population comprised 3000 individuals issued from 20 sires and 200 dams. Within each family, 10progenies belonged to the experimental population and were assigned phenotypes and marker genotypes and 5belonged to the selection population, only known on their marker genotypes. A total of 10,000 SNPs carried by 5chromosomes of 1 Morgan each were simulated. Eight QTL were created (1 quadri-allelic, 2 linked in phase, 2linked in repulsion, 1 imprinted and 2 epistatic). Random noise was added giving an heritability of 0.30. The markerdensity, LD and MAF were similar to real life parameters.
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