The Arabidopsis LHP1 protein colocalizes with histone H3 Lys27 trimethylation
2007
Zhang, Xiaoyu | Germann, Sophie | Blus, Bartlomiej J. | Khorasanizadeh, Sepideh | Gaudin, Valerie, | Jacobsen, Steven E.
Polycomb proteins are required for maintenance of silent chromatin states via histone H3 Lys27 trimethylation ( H3K27me3) in animals, but homologs are not found in plant genomes. Using a DamID- chip method, we found that the Arabidopsis thaliana chromodomain- containing protein LHP1 colocalizes with H3K27me3 genome- wide. The LHP1 chromodomain also binds H3K27me3 with high affinity, suggesting that LHP1 has functions similar to those of Polycomb.
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