Analysis of shared heritability in common disorders of the brain

Anttila, Verneri | Sullivan, Brenda | Finucane, Hilary | Walters, Walter | Bras, Jose | Duncan, Laramie | Price, Valentina | Falcone, Guido | Gormley, Padhraig | Malik, Rainer | Patsopoulos, Pat | Ripke, Stephan | Wei, Wei | Yu, Dongmei | Lee, Phil, L | Turley, Patrick | Grenier-Boley, Benjamin | Chouraki, Vincent | Kamatani, Yoichiro | Berr, Claudine | Letenneur, Luc | Hannequin, Didier | Amouyel, Philip | Boland, Anne | Deleuze, Jean-François | Duron, Emmanuelle | Vardarajan, N. | Reitz, Chris | Goate, Alison | Huentelman, Matthew | Kamboh, M. Ilyas | Larson, Lars | Rogaeva, Ekaterina | St George-Hyslop, Peter | Hakonarson, Hakon | Kukull, Walter | Li, Lindsay | Li, Lisa | Thomas, Thomas | Demirci, F. Yesim | Head, Eli | Hulette, Chris | Jicha, Gregory | Kauwe, John | Kaye, Jeffrey | Leverenz, James | Levey, Allan | Li, Andrew | Pankratz, Vernon | Poon, Wayne | Quinn, Joseph | Saykin, Andrew | Lo, Lon | Smit, Amanda | So, Joshua | Stern, Robert | van Deerlin, Vivianna | Li, Linda | Harold, Denise | Russo, Giancarlo | Rubinsztein, David, C. | Bayer, Anthony | Tsolaki, Magda | Proitsi, Petra | Fox, Nick | Hampel, Harald | Owen, Michael | Sim, Simon | Passmore, Peter | Morgan, Kevin | Markus, Mark | Schott, Jonathan | Kauffmann, Martin | Lupton, Michel | Hoffmann, Per | Kornhuber, Johannes | Lawlor, Brian | Mcquillin, Andrew | Al-Chalabi, Ammar | Bis, Joshua | Ruiz, Agustin | Boada, Mercè | Seshadri, Sudha | Beiser, Alexa | Rice, Kenneth | van Der Lee, Sven | de Jager, Philip | Geschwind, Dan | Riemenschneider, Matthias | Riedel-Heller, Helle | Rotter, Jerome | Ran, Gerhard | Hyman, Bradley, T. | Cruchaga, Carlos | Alegret, Montserrat | Winsvold, Bendik | Palta, Priit | Farh, Kai-How | Cuenca-Leon, Ester | Furlotte, Nicholas | Kurth, Tobias | Li, Lannie | Terwindt, Gisela | Freilinger, Tobias | Ran, Carol | Scott, Scott | Borck, Guntram | Adams, Hieab H.H. | Lehtimaki, Terho | Wedenoja, Juho | Buring, Julie | Hrafnsdottir, Maria | Hottenga, Jan | Penninx, Brenda | Artto, Ville | Kaunisto, Mari | Vepsäläinen, Salli | Martin, Nicholas, M | Montgomery, Grant, W. | Kurki, Mitja | Hämäläinen, Eija | Huang, Hailiang | Huang, Jie | Sandor, Cynthia | Webb, Caleb | Müller-Myhsok, Bertram | Schreiber, Stefan | Salomaa, Veikko | Lo, Eli | Göbel, Hartmut | Macaya, Alfons | Pozo-Rosich, Pat | Kaprio, Jaakko | Metspalu, Andres | Kubisch, Chris | Ferrari, Michel | Belin, Andrea | van den Maagdenberg, Arn M.J.M. | Zwart, John | Boomsma, Dorret, I. | Eriksson, Nicholas | Olesen, Ole | Chasman, Dan | Nyholt, Dale | Anney, Richard | Avbersek, Andreja | Bau, Larry | Berkovic, Samuel, F. | Bradfield, Jonathan | Buono, Russell | Catarino, Claudia | Cossette, Patrick | de Jonghe, Peter | Depondt, Chantal | Dlugos, Dennis | French, Jacqueline | Hjalgrim, Helle | Jamnadas-Khoda, Jennifer | Kälviäinen, Reetta | Kunz, Wolfram | Lerche, Holger | Leu, Costin | Li, Dick | Lo, Warren | Lowenstein, Dan | Mccormack, Mark | Møller, Rikke | Molloy, Anne | Ng, Ping-Wing | Oliver, Oliver | Privitera, Michael | Radtke, Rodney | Ruppert, Ann-Kathrin | Schachter, Steve | Schankin, Chris | Scheffer, Ingrid, E. | Schoch, Susan | Sisodiya, Sanjay | Smit, Philip | Sperling, Michael | Striano, Pasquale | Surges, Rainer | Visscher, Frank | Whelan, Chris | Zara, Federico | Heinzen, Erin | Marson, Anthony | Becker, Felicitas | Stroink, Hans | Zimprich, Fritz | Gasser, Thomas | Gibbs, Raphael | Heutink, Peter | Martinez, Matias | Morris, Huw | Sharma, Manu | Ryten, Mina | Mok, Kin | Pulit, Sara | Bevan, Steve | Holliday, Eli | Attia, John | Battey, Thomas | Boncoraglio, Giorgio | Thijs, Vincent | Chen, Wei | Mitchell, Braxton | Rothwell, Peter, M | Sharma, Pankaj | Cath, Cathie | Vicente, Astrid, M. | Kourkoulis, Chris | Pera, Joana | Mir, Miriam | Boraska Perica, Vesna | Thornton, Laura | Huckins, Laura | William Rayner, N. | Cath, Cathryn | Gratacòs, Mònica | Rybakowski, Filip | Keski-Rahkonen, Anna | Raevuori, Anu | Hudson, James | Reichborn-Kjennerud, Ted | Monteleone, Palmiero | Karwautz, Andreas | Männik, Katrin | Baker, Jessica | O’toole, Julie | Trace, Sara | Davis, Oliver | Helder, Sietske | Ehrlich, Stefan | Herpertz-Dahlmann, Beate | Danner, Dan | van Elburg, Annemarie | Clementi, Maurizio | Forzan, Monica | Docampo, Eli | Li, Jolanta | Hauser, Joanna | Tortorella, Alfonso | Maj, Mario | Gonidakis, Fragiskos | Tziouvas, Konstantinos | Papezova, Hana | Yilmaz, Zeynep | Wagner, Gudrun | Wood, Sarah | Herms, Stefan | Julià, Antonio | Rabionet, Raquel | Dick, Dan | Ripatti, Samuli | Andreassen, Andreas | Espeseth, Thomas | Lundervold, Astri | Steen, Vidar | Pinto, Dalila | Scherer, Stephen, W. | Aschauer, Harald | Schosser, Alexandra | Alfredsson, Lars | Padyukov, Leonid | Halmi, Katherine | Mitchell, James, Brian Alexander | Strober, Michael | Bergen, Andrew | Kaye, Walter | Szatkiewicz, Jin Peng | Cormand, Bru | Ramos, Josep Antoni | Sánchez-Mora, Cristina | Ribasés, Marta | Miguel, Miguel | Hervás, Amaia | Arranz, Maria | Haavik, Jan | Zayats, Tetyana | Johansson, Stefan | Williams, Nigel | Elia, Eli | Dempfle, Astrid | Rothenberger, Aribert | Kuntsi, Jonna | Oades, Robert, D. | Banaschewski, Tobias | Franke, Barbara | Buitelaar, Jan | Arias Vasquez, Alejandro | Doyle, Alysa, E. | Reif, Andreas | Lesch, Peter | Freitag, Chris | Rivero, Olga | Palmason, Haukur | Romanos, Marcel | Langley, Kate | Rietschel, Marcella | Witt, Stephanie | So, Soeren | Børglum, Anders, D. | Waldman, Irwin | Wilmot, Beth | Molly, Nikolas | Bau, Claiton H.D. | Crosbie, Jennifer | Schachar, Russell | Loo, Sandra, K. | Mcgough, James, J. | Grevet, Eugenio | Medland, Sarah, M | Robinson, Robin | Weiss, Wei | Bacchelli, Elena | Bailey, Anthony, J. | Bal, Vanessa | Battaglia, Agatino | Betancur, Catalina | Bolton, Patrick, F. | Cantor, Rita, M. | So, Pat | Dawson, Gerald | de Rubeis, Silvia | Duque, Frederico | Green, Andrew | Klauck, Sabine, M. | Leboyer, Marion | Levitt, Pat | Maestrini, Elena | Mane, Shrikant, M. | De-Luca, Dan | Parr, Jeremy, R. | Regan, Regina | Reichenberg, Abraham | Sandin, Sven | Vorstman, Jacob | Wassink, Thomas, H. | Wijsman, Ellen, M. | Cook, Edwin, H. | Santangelo, Susan, L. | Delorme, Richard | Rogé, Bernadette | Magalhaes, Tiago, R. | Arking, Dan, E. | Schulze, Thomas | Thompson, Robert, C. | Strohmaier, Jana | Matthews, Matthew | Melle, Ingrid | Morris, Derek | Blackwood, Douglas | Mcintosh, Andrew | Bergen, Sarah, E. | Schall, Martin | Jamain, Stéphane | Maaser, Anna | Fischer, Sascha | Reinbold, Céline | Fullerton, Janice | Grigoroiu-Serbanescu, Maria | Guzman-Parra, José | Mayoral, Fermin | Schofield, Peter, R. | Cichon, Sven | Mühleisen, Thomas | Degenhardt, Franziska | Schumacher, Johannes | Bauer, Michael | Mitchell, Philip, B. | Gershon, Elliot, S. | Rice, John, P. | Potash, James, B. | Zandi, Peter, P. | Craddock, Nick | Ferrier, I. Nicol | Alda, Martin | Rouleau, Guy, A. | Turecki, Gustavo | Ophoff, Roel | Pato, Carlos, N. | Anjorin, Adebayo | Stahl, Eli | Leber, Mark | Czerski, Piotr, M. | Edenberg, Howard, J. | Cruceanu, Cristiana | Jones, Ian, R. | Posthuma, Dan | Andlauer, Till F.M. | Forstner, Andreas | Streit, Fabian | Baune, Bernhard, T. | Air, Tracy | Sinnamon, Grant | Wray, Naomi, R. | Macintyre, Donald, J. | Porteous, David | Homuth, Georg | Rivera, Margarita | Grove, Jakob | Middeldorp, Chris | Hickie, Ian | Pergadia, Michele | Mehta, Divya | Smit, Johannes | Jansen, Rick | de Geus, Eco | Dunn, Erin | Li, Qingqin | Nauck, Matthias | Schoevers, Robert | Beekman, Aartjan Tf | Knowles, James | Viktorin, Alexander | Arnold, Paul | Cath, Cathy | Bedoya-Berrio, Gabriel | Bienvenu, O. 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KTH Royal Institute of Technology [Stockholm] (KTH) | Jefferson (Philadelphia University + Thomas Jefferson University) | University Medical Center Göttingen (UMG) | King‘s College London | Universität Heidelberg [Heidelberg] = Heidelberg University | Radboud University Medical Center [Nijmegen] (RadboudUMC) | Universitätsklinikum Frankfurt | Maastricht University [Maastricht] | Institute of Psychological Medicine and Clinical Neurosciences ; Cardiff University | Aarhus University [Aarhus] | Emory University [Atlanta, GA] | University of Iowa [Iowa City] | Universidade Federal do Rio Grande do Sul [Porto Alegre] (UFRGS) | The Hospital for sick children [Toronto] (SickKids) | University of California [Los Angeles] (UCLA) ; University of California (UC) | Hospital de Clínicas de Porto Alegre (HCPA) | Alma Mater Studiorum Università di Bologna = University of Bologna (UNIBO) | University of British Columbia [Canada] (UBC) | IRCCS Fondazione Stella Maris [Pisa] | Institut de Biologie Paris Seine (IBPS) ; Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS) | Neuroscience Paris Seine (NPS) ; Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Paris Seine (IBPS) ; Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS) | Duke University [Durham] | Universidade de Coimbra = University of Coimbra [Portugal] (UC) | Academic Centre on Rare Diseases (ACoRD) ; University College Dublin [Dublin] (UCD) | Our Lady's Children's Hospital Crumlin (OLCHC) | German Cancer Research Center - Deutsches Krebsforschungszentrum [Heidelberg] (DKFZ) | Institut Mondor de Recherche Biomédicale (IMRB) ; Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12) | Children’s Hospital Los Angeles [Los Angeles] | Yale University [New Haven] | Brown University | Institute of Neuroscience [Newcastle] (ION) ; Newcastle University [Newcastle] | Department of Medical Epidemiology and Biostatistics (MEB) ; Karolinska Institutet [Stockholm] | Division of Medical Genetics [Seattle] ; University of Washington [Seattle] | University of Illinois [Chicago] (UIC) ; University of Illinois System | Maine Medical Center Research Institute (MMCRI) | Génétique humaine et fonctions cognitives - Human Genetics and Cognitive Functions (GHFC (UMR_3571 / U-Pasteur_1)) ; Institut Pasteur [Paris] (IP)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS) | Centre d’Etudes et de Recherches en Psychopathologie et Psychologie de la Santé (CERPPS) ; Université Toulouse - Jean Jaurès (UT2J) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Toulouse Mind & Brain Institut (TMBI) ; Université Toulouse - Jean Jaurès (UT2J) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3) ; Université de Toulouse (UT)-Université Toulouse - Jean Jaurès (UT2J) ; Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3) ; Université de Toulouse (UT) | Johns Hopkins University School of Medicine [Baltimore] | Ludwig Maximilian University [Munich] = Ludwig Maximilians Universität München (LMU) | University of Michigan [Ann Arbor] ; University of Michigan System | Department of Genetic Epidemiology in Psychiatry [Mannhein] ; Universität Heidelberg [Heidelberg] = Heidelberg University-Central Institute of Mental Health Mannheim | University of Dundee | National University of Ireland [Galway] (NUI Galway) | University Hospital Basel [Basel] | Neuroscience Research Australia (NeuRA) | Forschungszentrum Jülich GmbH | Centre de recherche de Jülich | Jülich Research Centre (FZJ) ; Helmholtz-Gemeinschaft = Helmholtz Association | UNSW Faculty of Medicine [Sydney] ; University of New South Wales [Sydney] (UNSW) | University of Chicago | Washington University in Saint Louis (WUSTL) | Johns Hopkins University (JHU) | Johns Hopkins Bloomberg School of Public Health [Baltimore] ; Johns Hopkins University (JHU) | Dalhousie University [Halifax] | Montreal Neurological Institute and Hospital ; McGill University = Université McGill [Montréal, Canada] | McGill University = Université McGill [Montréal, Canada] | State University of New York (SUNY) | University Hospital of Cologne [Cologne] | University of Adelaide | James Cook University (JCU) | Institute for Molecular Bioscience ; The University of Queensland (UQ [All campuses : Brisbane, Dutton Park Gatton, Herston, St Lucia and other locations]) | Greifswald University Hospital | The University of Queensland (UQ [All campuses : Brisbane, Dutton Park Gatton, Herston, St Lucia and other locations]) | The University of Sydney | Queensland University of Technology [Brisbane] (QUT) | University Medical Center Groningen [Groningen] (UMCG) | University of Calgary | University Health Network [Toronto, ON, Canada] | Universidad de Antioquia = University of Antioquia [Medellín, Colombia] | Universidade de São Paulo = University of São Paulo (USP) | Ospedale San Raffaele | University of Amsterdam [Amsterdam] = Universiteit van Amsterdam (UvA) | University of Groningen [Groningen] | Yale School of Medicine [New Haven, Connecticut] (YSM) | Academic Medical Center - Academisch Medisch Centrum [Amsterdam] (AMC) ; University of Amsterdam [Amsterdam] = Universiteit van Amsterdam (UvA) | CHU Pitié-Salpêtrière [AP-HP] ; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU) | Harvard Medical School [Boston] (HMS) | University of Cape Town | Cold Spring Harbor Laboratory (CSHL) | University of California [Irvine] (UC Irvine) ; University of California (UC) | Universidad de Sevilla = University of Seville | University of Florida [Gainesville] (UF) | University of Denver | Purdue University [West Lafayette] | Centre Hospitalier Universitaire Vaudois = Lausanne University Hospital [Lausanne] (CHUV) | Moscow Institute of Physics and Technology [Moscow] (MIPT) | Sunnybrook Health Sciences Centre [Toronto] (Sunnybrook) | Federal Institute of São Paulo (IFSP) | Democritus University of Thrace (DUTH) | Universiteit Gent = Ghent University = Université de Gand (UGENT) | Warszawski Uniwersytet Medyczny [Polska] = Medical University of Warsaw [Poland] = Université de Médecine de Varsovie [Pologne] | Sorbonne Université - Faculté de Médecine - Département d'Enseignement et de Recherche en Médecine Générale ; Sorbonne Université (SU) | Universitätsklinikum Essen [Universität Duisburg-Essen] (Uniklinik Essen) | Institut de génétique et biologie moléculaire et cellulaire (IGBMC) ; Université Louis Pasteur - Strasbourg I-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS) | Vanderbilt University Medical Center [Nashville] ; Vanderbilt University [Nashville] | Institute of Mental Health [Singapore] | Universidad de Cantabria [Santander] = University of Cantabria [Spain] = Université de Cantabrie [Espagne] (UC / UniCan) | Tel Aviv University (TAU) | University College Cork (UCC) | University of Rochester [USA] | Statens Serum Institut [Copenhagen] | Софийски университет = Sofia University | Russian Academy of Sciences [Moscow] (RAS) | Latvian Biomedical Research and Study Centre [Rīga] | Vilnius University [Vilnius] | Nanyang Technological University [Singapour] (NTU) | Department of Life Sciences ; Imperial College London | Jena University Hospital [Jena] | Oxford University Hospitals NHS Trust ; University of Oxford | Schizophrenia Research Institute [Sydney] | Faculty of Science, Medicine and Health [Wollongong] ; University of Wollongong [Australia] | City University of Hong Kong [Hong Kong] (CUHK) | Lawrence Berkeley National Laboratory [Berkeley] (LBNL) | This work was supported by grants 1R01MH10764901 and 5U01MH09443203 from the National Institute of Mental Health, as well as the Orion Farmos Research Foundation (V.A.) and the Fannie and John Hertz Foundation (H.K.F.). Consortium specific funding is detailed in the supplementary materials (“Study-specific acknowledgments”). | ANR-11-LABX-0009,DISTALZ,Développement de stratégies innovantes pour une approche transdisciplinaire de la maladie d'Alzheime(2011)