Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

2018

Demenais, Florence | Margaritte-Jeannin, Patricia | Barnes, Kathleen | Cookson, William, O. C. M. | Altmüller, Janine | Ang, Wei | Barr, R. Graham | Beaty, Terri | Becker, Allan | Beilby, John | Bisgaard, Hans | Bjornsdottir, Unnur Steina | Bleecker, Eugene, R. | Bønnelykke, Klaus | Boomsma, Dorret | Bouzigon, Emmanuelle | Brightling, Christopher, E. | Brossard, Myriam | Brusselle, Guy | Burchard, Esteban | Burkart, Kristin | Bush, Andrew | Chan-Yeung, Moira | Chung, Kian Fan | Couto Alves, Alexessander | Curtin, John | Custovic, Adnan | Daley, Denise | de Jongste, Johan | Del-Rio-Navarro, Blanca | Donohue, Kathleen | Duijts, Liesbeth | Eng, Celeste | Eriksson, Johan | Farrall, Martin | Fedorova, Yuliya | Feenstra, Bjarke | Ferreira, Manuel | Freidin, Maxim, B. | Gajdos, Zofia | Gauderman, Jim | Gehring, Ulrike | Geller, Frank | Genuneit, Jon | Gharib, Sina | Gilliland, Frank | Granell, Raquel | Graves, Penelope, E. | Gudbjartsson, Daniel | Haahtela, Tari | Heckbert, Susan | Heederik, Dick | Heinrich, Joachim | Heliövaara, Markku | Henderson, John | Himes, Blanca | Hirose, Hiroshi | Hirschhorn, Joel | Hofman, Albert | Holt, Patrick | Hottenga, Jouke | Hudson, Thomas, J. | Hui, Jennie | Imboden, Medea | Ivanov, Vladimir | Jaddoe, Vincent | James, Alan | Janson, Christer | Järvelin, Marjo-Riitta | Jarvis, Deborah | Jones, Graham | Jonsdottir, Ingileif | Jousilahti, Pekka | Kabesch, Michael | Kähönen, Mika | Kantor, David | Karunas, Alexandra | Khusnutdinova, Elza | Koppelman, Gerard, H. | Kozyrskyj, Anita | Kreiner, Eskil | Kubo, Michiaki | Kumar, Rajesh | Kumar, Ashish | Kuokkanen, Mikko | Lahousse, Lies | Laitinen, Tarja | Laprise, Catherine | Lathrop, Mark | Lau, Susanne | Lee, Young-Ae | Lehtimäki, Terho | Letort, Sébastien | Levin, Albert | Li, Guo | Liang, Liming | Loehr, Laura, R. | London, Stephanie | Loth, Daan | Manichaikul, Ani | Marenholz, Ingo | Martinez, Fernando, D. | Matheson, Melanie | Mathias, Rasika | Matsumoto, Kenji | Mbarek, Hamdi | Mcardle, Wendy | Melbye, Mads | Melen, Erik | Meyers, Deborah, A. | Michel, Sven | Mohamdi, Hamida | Musk, Arthur | Myers, Rachel | Nieuwenhuis, Maartje | Noguchi, Emiko | O’connor, George | Ogorodova, Ludmila | Palmer, Cameron | Palotie, Aarno | Park, Julie | Pennell, Craig | Pershagen, Goran | Polonikov, Alexey | Postma, Dirkje, S. | Probst-Hensch, Nicole, M | Puzyrev, Valery | Raby, Benjamin | Raitakari, Olli | Ramasamy, Adaikalavan | Rich, Stephen | Robertson, Colin | Romieu, Isabelle | Salam, Muhammad | Salomaa, Veikko | Schlünssen, Vivi | Scott, Robert, A. | Selivanova, Polina | Sigsgaard, Torben | Simpson, Angela | Siroux, Valérie | Smith, Lewis | Solodilova, Maria | Standl, Marie | Stefansson, Kari | Strachan, David, P. | Stricker, Bruno | Takahashi, Atsushi | Thompson, Philip | Thorleifsson, Gudmar | Thorsteinsdottir, Unnur | Tiesler, Carla | Torgerson, Dara | Tsunoda, Tatsuhiko | Uitterlinden, Andre | van Der Valk, Ralf | Vaysse, Amaury | Vedantam, Sailaja | von Berg, Andrea | von Mutius, Erika | Vonk, Judith, M. | Waage, Johannes | Wareham, Nick | Weiss, Scott | White, Wendy | Wickman, Magnus | Widén, Elisabeth | Willemsen, Gonneke | Williams, L. Keoki | Wouters, Inge | Yang, James | Zhao, Jing Hua | Moffatt, Miriam, F. | Ober, Carole, C. | Nicolae, Dan | Fondation Jean-Dausset-CEPH, INSERM U946 ; Institut National de la Santé et de la Recherche Médicale (INSERM) | Variabilité Génétique et Maladies Humaines (U946) ; Institut Universitaire d'Hématologie (IUH) ; Université Paris Diderot - Paris 7 (UPD7)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM) | Department of Medicine [Aurora, CO, USA] ; University of Colorado [Denver] | National Heart and Lung Institute (NHLI) ; Imperial College London | Cologne Center for Genomics (CCG) ; Cologne Center for Genomics-Universität zu Köln = University of Cologne | Johns Hopkins University (JHU) | Pediatrics and Child Health ; University of Manitoba [Winnipeg] | University of Arizona | King‘s College London | Méthodologie statistique et épidémiologie génétique de maladies multifactorielles ; Université d'Évry-Val-d'Essonne (UEVE)-Institut National de la Santé et de la Recherche Médicale (INSERM) | Department of Respiratory Medicine and Thoracic Surgery ; University of Leicester-Institute for Lung Health | Ghent University Hospital | Department of Paediatric Respiratory Medicine ; Imperial College London-Royal Brompton Hospital-National Heart and Lung Institute [UK] | Airway Disease Section, National Heart and Lung Institute ; Imperial College London | Imperial College London | The Generation R Study group ; Erasmus University Medical Centre | Medstar Research Institute ; Medstar Research Institute | The Wellcome Trust Centre for Human Genetics [Oxford] ; University of Oxford | Université Paris-Sorbonne - Paris 4 - École supérieure du professorat et de l'éducation - Académie de Paris (ESPE Paris) ; Université Paris-Sorbonne (UP4) | Population Genetics Laboratory [Tomsk, Russia] ; Research Institute for Medical Genetics [Tomsk, Russia] | University of Southern California (USC) | Universiteit Utrecht / Utrecht University [Utrecht] | Institute of Epidemiology ; Universität Ulm - Ulm University [Ulm, Allemagne] | MRC Integrative Epidemiology Unit [Bristol, Royaume-Uni] (MRC IEU) ; University of Bristol [Bristol] | Arizona Respiratory Center | Helsinki University Hospital [Finland] (HUS) | Division of Occupational and Environmental Health, Institute for Risk Assessment (IRAS) ; Universiteit Utrecht / Utrecht University [Utrecht] | Ludwig Maximilian University [Munich] = Ludwig Maximilians Universität München (LMU) | National Institute of Health and Welfare | MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine ; MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine | Erasmus University Medical Center [Rotterdam] (Erasmus MC) | Department of Mathematics, University of Warwick ; Warwick Mathematics Institute (WMI) ; University of Warwick [Coventry]-University of Warwick [Coventry] | Sir Charles Gairdner Hospital | Swiss Tropical and Public Health Institute [Basel] | The Generation R Study; Pediatrics; Epidemiology ; The Generation R Study; Pediatrics; Epidemiology | Uppsala University | Institute of Health Sciences and Biocenter Oulu ; University of Oulu [Finland] = Oulun yliopisto [Suomi] = Université d'Oulu [Finlande] | Tampere University Hospital | Institute of Biochemistry and Genetics of Ufa Scientific Centre ; Russian Academy of Sciences [Moscow] (RAS) | Pediatric Pulmonology, Allergology & Epidemiology ; University of Groningen [Groningen]-University Medical Center Groningen [Groningen] (UMCG)-Beatrix Children's Hospital-Groningen Research Institute for Asthma and COPD | National Center for Atmospheric Research [Boulder] (NCAR) | Epidemiology & Public Health ; Swiss Tropical and Public Health Institute [Basel]-Medical School University of Basel | Department of Respiratory Medicine ; Imperial College London | Departments of Pulmonary Medicine and Medical Genetics | Université du Québec à Chicoutimi (UQAC) | McGill University and Genome Quebec Innovation Centre | Department of Pediatric Pneumology and Immunology ; Charité - UniversitätsMedizin = Berlin University Medicine | Max Delbrück Center for Molecular Medicine [Berlin] (MDC) ; Helmholtz-Gemeinschaft = Helmholtz Association | Faculty of Medicine and Life Sciences [Tampere] ; University of Tampere [Finland] | Laboratoire des interactions plantes micro-organismes (LIPM) ; Institut National de la Recherche Agronomique (INRA)-Centre National de la Recherche Scientifique (CNRS) | China Agricultural University (CAU) | Harvard School of Public Health | Department of Epidemiology ; University of North Carolina [Chapel Hill] (UNC) ; University of North Carolina System (UNC)-University of North Carolina System (UNC)-UNC Gillings School of Global Public Health-Carolina Center for Genome Sciences | National Institute for Environmental Health Sciences Research Triangle Park ; National Institute for Environmental Health Sciences Research Triangle Park | National Institute for Materials Science (NIMS) | Dept. of Epidemiology Research ; Statens Serum Institut [Copenhagen] | Institute of Environmental Medicine [Stockholm, Sweden] ; Karolinska Institutet [Stockholm]-Karolinska University Hospital [Stockholm]-Astrid Lindgren Children's Hospital | Center for Human Genomics ; Wake Forest University | Institut National de la Santé et de la Recherche Médicale (INSERM) | Université de Tsukuba = University of Tsukuba | Head of Medical Sequencing ; Head of Medical Sequencing | Institute of environmental medicine ; Karolinska Institute | Respiratory Epidemiology and Public Health ; Imperial College London-School of public health ; The University of Hong Kong (HKU)-The University of Hong Kong (HKU)-MRC-HPA Centre for Environment and Health | Centre International de Recherche contre le Cancer (CIRC) | Department of Chronic Disease Prevention ; National Institute for Health and Welfare [Helsinki] | Aarhus University [Aarhus] | Institute of Metabolic Science ; MRC | Section of Environment Occupation & Health ; Aarhus University [Aarhus] | University of Manchester [Manchester] | Epidémiologie et Biostatistique ; Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Santé et de la Recherche Médicale (INSERM) | deCODE Genetics ; deCODE genetics [Reykjavik] | Population Health Sciences and Education ; St George's University of London | Drug Safety Unit ; Inspectorate for Health Care | Tohoku University [Sendai] | Department of Oceanography ; University of Hawai‘i [Mānoa] (UHM) | University of California [San Francisco] (UC San Francisco) ; University of California (UC) | Asthma and Allergy Department ; University Children's Hospital-Ludwig-Maximilians University [Munich] (LMU) | IT University of Copenhagen (ITU) | MRC Epidemiology Unit, Institute of Metabolic Science ; University of Cambridge [UK] (CAM) | Sachs’ Children and Youth Hospital [Stockholm, Sweden] | Genetic Epidemiology Unit ; Erasmus University Medical Center [Rotterdam] (Erasmus MC) | MRC Epidemiology Unit, Institute of Metabolic Science ; Addenbrooke's Hospital | University of Illinois [Chicago] (UIC) ; University of Illinois System | Titu Maiorescu University Bucharest ; Titu Maiorescu University = Universitatea Titu Maiorescu [Buchares] (UTM)