Lumpy skin disease in Ethiopia: Seroprevalence study across different agro-climate zones
2012
Gari, G. | Grosbois, V. | Waret-Szkuta, A. | Babiuk, S. | Jacquiet, Philippe, P. | Roger, F. | Natl Anim Hlth Diagnost & Invest Ctr ; Partenaires INRAE | Animal et gestion intégrée des risques (UPR AGIRs) ; Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad) | Ecole Nationale Vétérinaire de Toulouse (ENVT) ; Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT) | Natl Ctr Foreign Anim Dis ; Partenaires INRAE | Interactions hôtes-agents pathogènes [Toulouse] (IHAP) ; Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT) ; Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP) ; Université de Toulouse (UT)-Université de Toulouse (UT) | General Directorate for Development and International Cooperation, French Ministry of Foreign Affairs, French Embassy in Ethiopia through the PSF [2003-24 LABOVET]
International audience
Show more [+] Less [-]English. A cross-sectional study was conducted to estimate the seroprevalence of lumpy skin disease (LSD) in the different agro-climatic zones prevailing in Ethiopia. A total of 2368 serum samples were collected from 42 kebeles located in 15 districts and tested using indirect fluorescent antibody test (IFAT) and virus neutralization test (VNT). The herd and animal true LSD serological prevalence were estimated in each agro-climate zone using a Bayesian model. The intra-cluster correlation coefficient (ICC) was evaluated using a random-effect model. According to the serological prevalence estimations, LSD affected differently the three agro-climatic zones considered. Herd level seroprevalence was higher in the midland agro-climate zone 64% (95% CI: 53-74) as compared to the highland 26% (95% CI: 17-36) and the lowland 50% (95% CI: 40-60) agro-climates. Animal level seroprevalence in infected herds was also higher in the midland agro-climate zone 31% (95% CI: 24-40) than in the highland and lowland zones (24% (95% CI: 18-31) and 23% (95% CI: 18-29), respectively). Higher ICC value in the highland agro-climate zone implies that increased sample sizes should be particularly required for this zone in future studies to estimate LSD prevalence or incidence with a desired precision level. This seroprevalence study also suggests that the prevalence of LSD infection in Ethiopia is higher than what has been previously reported. In the light of these updated estimations, we discuss options to trigger appropriate control measures in the future. (C) 2012 Elsevier B.V. All rights reserved.
Show more [+] Less [-]AGROVOC Keywords
Bibliographic information
This bibliographic record has been provided by Institut national de la recherche agronomique