Shifting the limits in wheat research and breeding using a fully annotated reference genome
2018
International Wheat Genome Sequencing Consortium (iwgsc), . | Bellec, Arnaud | Berges, Helene | Vautrin, Sonia | Alaux, Michael | Alfama, Françoise | Adam-Blondon, Anne-Francoise | Flores, Raphaël | Guerche, Claire | Letellier, Thomas | Loaec, Mikaël | Quesneville, Hadi | Appels, Rudi | Rigault, Philippe | Choulet, Frédéric | Josselin, Ambre-Aurore | Balfourier, François | Paux, Etienne | Rimbert, Hélène | Guilhot, Nicolas | Leroy, Philippe | Arnaud, Dominique | Chalabi, Smahane | Sourdille, Pierre | Darrier, Benoît | Centre National de Ressources Génomiques Végétales (CNRGV) ; Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) | Unité de Recherche Génomique Info (URGI) ; Institut National de la Recherche Agronomique (INRA) | Collège de Direction (CODIR) ; Institut National de la Recherche Agronomique (INRA) | Gydle Inc ; Partenaires INRAE | Génétique Diversité et Ecophysiologie des Céréales (GDEC) ; Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]) | Institut de Génétique, Environnement et Protection des Plantes (IGEPP) ; Institut National de la Recherche Agronomique (INRA)-Université de Rennes (UR)-AGROCAMPUS OUEST | UAR 1306 Direction du Système d'Information-Unité d'Appui ; Institut National de la Recherche Agronomique (INRA) | Institut des Sciences des Plantes de Paris-Saclay (IPS2 (UMR_9213 / UMR_1403)) ; Institut National de la Recherche Agronomique (INRA)-Université Paris-Sud - Paris 11 (UP11)-Université Paris Diderot - Paris 7 (UPD7)-Université d'Évry-Val-d'Essonne (UEVE)-Centre National de la Recherche Scientifique (CNRS) | Agence Nationale pour la Recherche [ANR-11-BSV5-0015-Ploid-Ploid; ANR-16-TERC-0026-01-3DWHEAT]; Agriculture and Agri-Food Canada; Alberta Wheat Development Commission through the Canadian Applied Tricticum Genomics (CTAG2); Australian Government, Department of Industry, Innovation, Climate Change, Science, Research, and Tertiary Education, Australia China Science and Research Fund Group Mission [ACSRF00542]; Australian Research Council Centre of Excellence in Plant Energy Biology [CE140100008]; Australian Research Council [FL140100179]; Bayer CropScience; Biotechnology and Biological Sciences Research Council (BBSRC) [BB/J00426X/1; BB/J004669/1; BB/P016855/1; BB/J003557/1; BB/M014045/1]; Canada First Research Excellence Fund through the Designing Crops for Global Food Security initiative at the University of Saskatchewan; Council for Agricultural Research and Economics, Italy, through CREA-Interomics; Department of Biotechnology, Ministry of Science and Technology, Government of India [BT/IWGSC/03/TF/2008]; DFG [SFB924]; European Commission through the TriticeaeGenome [FP7-212019]; France Genomique Genome Canada through the CTAG2 project [ANR-10-INBS-09]; Genome Prairie through the CTAG2 project; German Academic Exchange Service (DAAD) PPP Australien [1j16]; German Federal Ministry of Food and Agriculture [2819103915 WHEATSEQ]; German Ministry of Education and Research [031A536 de.NBI]; Global Institute for Food Security Genomics and Bioinformatics fund; Gordon and Betty Moore Foundation [GBMF4725]; Grain Research Development Corporation (GRDC) Australia; Graminor AS NFR project [199387]; illumina; INRA, French National Institute for Agricultural Research; International Wheat Genome Sequencing Consortium; Israel Science Foundation [999/12; 1137/17; 1824/12]; Junta de Andalucia, Spain [P12-AGR-0482]; MINECO (Spanish Ministry of Economy, Industry, and Competitiveness) [BIO2011-15237-E]; Ministry of Agriculture, Forestry, and Fisheries of Japan through Genomics for Agricultural Innovation [KGS-1003]; Ministry of Agriculture, Forestry, and Fisheries of Japan through Genomics-based Technology for Agricultural Improvement [NGB-1003]; Ministry of Education and Science of Russian Federation [RFMEFI60414X0106; RFMEFI60414 X0107]; Ministry of Education, Youth, and Sport of the Czech Republic [LO1204]; Nisshin Flour Milling, Inc.; National Research Council of Canada; Norwegian University of Life Sciences (NMBU) NFR project [199387]; National Science Foundation, United States [1339389; DBI-0701916; IIP-1338897]; Russian Science Foundation [14-14-00161]; Saskatchewan Ministry of Agriculture through the CTAG2 project; Saskatchewan Wheat Development Commission through the CTAG2 project; Czech Science Foundation [521/06/1723; 521-08-1629; P501/10/1740; P501/12/2554; P501/12/G090; 14-07164S; 13-08786S]; Research Council of Norway [199387]; U.S. Department of Agriculture NIFA [2008-35300-04588]; University of Zurich; Western Grains Research Foundation; Western Grains Research Foundation National Wheat Improvement Program; Winifred-Asbjornson Plant Science Endowment Fund;French Government [ANR-10-BTBR-03]; FranceAgriMer [2011-0971; 2013-0544]; INRA; NBI Computing infrastructure for Science (CiS) group through the HPC cluster | ANR-11-BSV6-0015,PLOID-PLOID-WHEAT,Caractérisation des réponses à la polyploïdie et l'aneuploïdie chez les angiospermes, utilisant le modèle blé(2011) | ANR-16-TERC-0026,3DWheat,Epigénome, transcriptome, architecture de la chromatine: une étude en trois dimensions de la réponse au stress thermique chez le blé(2016) | European Project: 212019,EC:FP7:KBBE,FP7-KBBE-2007-1,TRITICEAEGENOME(2008)
International audience
Show more [+] Less [-]English. An annotated reference sequence representing the hexaploid bread wheat genome in 21 pseudomolecules has been analyzed to identify the distribution and genomic context of coding and noncoding elements across the A, B, and D subgenomes. With an estimated coverage of 94% of the genome and containing 107,891 high-confidence gene models, this assembly enabled the discovery of tissue- and developmental stage-related coexpression networks by providing a transcriptome atlas representing major stages of wheat development. Dynamics of complex gene families involved in environmental adaptation and end-use quality were revealed at subgenome resolution and contextualized to known agronomic single-gene or quantitative trait loci. This community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding.
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