Establishment of pregnancy in sheep and pigs [review]. [Conference lecture]
1989
Bazer, F.W. (Florida Univ., Gainesville (USA). Dept. of Animal Science)
Sheep conceptuses secrete a protein, ovine trophoblast protein-1 (oTP-1), between days 10 and 21 of gestation, that is responsible for the establishment of pregnancy. Porcine conceptuses secrete oestrogens between days 10 and 15 of pregnancy that are essential for establishment of pregnancy. Conceptus secretory proteins of sheep and pigs include proteins that have antiviral activity and are considered interferons. In sheep, oTP-1 has antiluteolytic, immunosuppressive, antiviral and possibly antiproliferative properties. The specific pig conceptus secretory protein(s) possessing antiviral activity has not been established. Unlike oTP-1, however, pig interferon-like protein(s) does not appear to possess antiluteolytic activity.
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