Comparison of the effect of dietary meat versus dietary soybean protein on plasma lipids of hyperlipidemic individuals
1980
Holmes, W.L. | Rubel, G.B. | Hood, S.S. (Lankenua Hospital, Philadelphia (USA). Dept. of Research)
This report is concerned with two studies comparing the effect of dietary meat and dietary soybean protein on plasma lipids in hyperlipoproteinemic individuals. In the first study the mean total plasma cholesterol was reduced 13 per cent during the first three week dietary sequence using a prudent low-fat, low-cholesterol diet containing meat. Substituting soybean protein for the meat protein in the second dietary sequence had very little additional effect. The major cholesterol changes occurred in the LDL and VLDL fractions. In the second study, which employed a crossover design, the diet was planned to allow essentially complete replacement of all animal protein with soybean protein without any appreciable changes in all other dietary components. Both diets significantly lowered mean total plasma cholesterol during the first three week dietary sequence, the meat diet by 18 per cent and the soy diet by 19 per cent. Crossing over the diets for an additional 3 weeks had no further effect. Again the major change occurred in the LDL and VLDL fractions
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