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From Prediction to Function Using Evolutionary Genomics: Human-Specific Ecotypes of Lactobacillus reuteri Have Diverse Probiotic Functions

2015

Spinler, Jennifer K. | Amrita SontakkeauthorTexas Childrens Microbiome Center, Department of Pathology, Texas Childrens Hospital, Houston, TX Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX | Emily B. HollisterauthorTexas Childrens Microbiome Center, Department of Pathology, Texas Childrens Hospital, Houston, TX Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX | Susan F. VenableauthorTexas Childrens Microbiome Center, Department of Pathology, Texas Childrens Hospital, Houston, TX Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX | Phaik Lyn OhauthorDepartment of Food Science and Technology, University of Nebraska, Lincoln | Miriam A. BalderasauthorDepartment of Molecular Virology & Microbiology, Baylor College of Medicine, Houston, TX | Delphine M.A. SaulnierauthorTexas Childrens Microbiome Center, Department of Pathology, Texas Childrens Hospital, Houston, TX Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX Present address: Department of Gastrointestinal Microbiology, German Institute of Human Nutrition, Nuthetal, Germany. | Toni-Ann MistrettaauthorTexas Childrens Microbiome Center, Department of Pathology, Texas Childrens Hospital, Houston, TX Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX | Sridevi DevarajauthorTexas Childrens Microbiome Center, Department of Pathology, Texas Childrens Hospital, Houston, TX Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX | Jens WalterauthorDepartment of Food Science and Technology, University of Nebraska, Lincoln Present address: Departments of Agricultural, Food, & Nutritional Science and Biological Sciences, University of Alberta, Edmonton, AB, Canada. | James VersalovicauthorTexas Childrens Microbiome Center, Department of Pathology, Texas Childrens Hospital, Houston, TX Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX Department of Molecular Virology & Microbiology, Baylor College of Medicine, Houston, TX | Sarah K. HighlanderauthorDepartment of Molecular Virology & Microbiology, Baylor College of Medicine, Houston, TX Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX Present address: Genomic Medicine, J. Craig Venter Institute, La Jolla, CA.


Bibliographic information
Other Subjects
Coevolution; Multigene family; Interleukin-13; Tumor necrosis factors; Interleukin-7; Anti-inflammatory; Immunostimulatory; Microarray technology; Host-based evolution; Interleukin-5; Reuterin; Interleukin-12; Lactobacillus reuteri; Pocr transcriptional regulation; Chemokine ccl2
Language
English
Type
Text; Journal Article

2016-11-15
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