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Towards the computational design and engineering of enzyme enantioselectivity: A case study by a carbonyl reductase from Gluconobacter oxydans

2015

Deng, Jian | Zhiqiang YaoauthorState Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, China | Kangling ChenauthorState Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, China | Y. Adam YuanauthorDepartment of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117543, Singapore | Jinping LinauthorState Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, China | Dongzhi WeiauthorState Key Laboratory of Bioreactor Engineering, New World Institute of Biotechnology, East China University of Science and Technology, Shanghai 200237, China


Bibliographic information
Other Subjects
Site-directed mutagenesis; Carbonyl reductase; Enantiomers; Enantiorecognition; Nad (coenzyme); Molecular dynamics; Opbe; Improved enantioselectivity; Computational design; Gluconobacter oxydans; Crystal structure
Language
English
Type
Text; Journal Article

2016-11-15
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