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Simultaneous quantitative determination of seven novel tyrosine kinase inhibitors in plasma by a validated UPLC-MS/MS method and its application to human microsomal metabolic stability study

2020

Ezzeldin, Essam | Iqbal, Muzaffar | Herqash, Rasheed N. | ElNahhas, Toqa


Bibliographic information
Journal of chromatography
Volume 1136 Issue 12 ISSN 1570-0232
Publisher
Elsevier B.V.
Pagination
121851
Other Subjects
Validation; Tyrosine kinase inhibitors; Acetonitrile; Ultra-performance liquid chromatography; Ammonium acetate; Methyl ethers; Liquid-liquid extraction; Metabolic stability; Ethyl acetate; Therapeutics; Electrospray ionization mass spectrometry; Protein-tyrosine kinases; Uplc-ms/ms; Plasma
Language
English

2020-02-15
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