Microwave-assisted oxidation of indan-1-ones into ninhydrins
2015
Marminon, Christelle | Nacereddine, Abdelhamid | Bouaziz, Zouhair | Nebois, Pascal | Jose, Joachim | Le Borgne, Marc
A simple and general microwave-assisted selenium oxidation has been developed for the synthesis of substituted ninhydrins from indan-1-ones in order to access to indeno[1,2-b]indoles substituted on the A ring. This efficient and convenient oxidation, using selenium dioxide under microwave irradiations, afforded mono- and di-substituted ninhydrins in a single step reaction with good yields.
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