Effect of the Benzylic Structure of Lignan on Antioxidant Activity
2007
YAMAUCHI, Satoshi | SUGAHARA, Takuya | MATSUGI, Junko | SOMEYA, Tatsushi | Masuda, Toshiya | KISHIDA, Taro | AKIYAMA, Koichi | MARUYAMA, Masafumi
The effect of the benzylic structure of lignan on antioxidant activity was evaluated. Secoisolariciresinol (1) and 3,4-bis(4-hydroxy-3-methoxybenzyl)tetrahydrofuran (2), which have two secondary benzylic positions without oxygen, showed the highest antioxidant activity. Optically active verrucosin (4) was synthesized for the first time in this experiment.
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