Using a flexible shaft agitator to enhance the rheology of a complex fungal fermentation culture
2016
Ghobadi, Narges | Ogino, Chiaki | Ogawa, Tomohiro | Ohmura, Naoto
The rheology behavior of biological fluids particularly when the viscosity is high and rheology is complex, is an important issue to understand, particularly for studies in mass-transfer and for solving technical problems with mixing in stirred bioreactors. In this paper, the use of a Swingstir® impeller during the fermentation of Aspergillus oryzae resulted in decreases from the parameters of a power-law model, in viscosity and in the thixotropic behavior of a cultivation broth. The results showed that both the K L a and the alpha amylase activity were improved when using the Swingstir® in comparison with Fullzone® impeller (FZ) at the same level of energy consumption. Increasing the pellet porosity during mixing via the Swingstir® resulted in increases in oxygen mass transfer and the average shear stress.
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