Experimental ocular Toxocara canis and Ascaris suum infection: In vivo and in vitro study
1983
John, T. | Donnelly, J.J. | Rockey, J.H.
Toxocara canis, Ascaris suum, eosinophil interaction with second-stage larvae studied in guinea pig model and in culture, larvae in culture moved freely within surrounding sheath, escape from sheath is potential mechanism whereby parasite evades host inflammatory response, discarded sheath may act as focus of intraocular eosinophil granuloma while larva is free at another site, toxic effects of eosinophil mediators on eye may cause damage to ocular tissue while eosinophils isolate and destroy larvae
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