The impact of cefepime as first line therapy for neutropenic fever on Clostridium difficile rates among hematology and oncology patients
2013
Muldoon, Eavan G. | Epstein, Lauren | Logvinenko, Tanya | Murray, Susan | Doron, Shira I. | Snydman, David R.
After changing empiric treatment of febrile neutropenia from meropenem to cefepime, the effect on Clostridium difficile infection (CDI) was investigated. The change was assessed using an autoregressive model. A significant increase in CDI rates occurred following the introduction of cefepime. There may be an association between increased cefepime usage and CDI.
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