HGVbaseG2P: a central genetic association database
2009
Thorisson, Gudmundur A. | Lancaster, Owen | Free, Robert C. | Hastings, Robert K. | Sarmah, Pallavi | Dash, Debasis | Brahmachari, Samir K. | Brookes, Anthony J.
The Human Genome Variation database of Genotype to Phenotype information (HGVbaseG2P) is a new central database for summary-level findings produced by human genetic association studies, both large and small. Such a database is needed so that researchers have an easy way to access all the available association study data relevant to their genes, genome regions or diseases of interest. Such a depository will allow true positive signals to be more readily distinguished from false positives (type I error) that fail to consistently replicate. In this paper we describe how HGVbaseG2P has been constructed, and how its data are gathered and organized. We present a range of user-friendly but powerful website tools for searching, browsing and visualizing G2P study findings. HGVbaseG2P is available at http://www.hgvbaseg2p.org.
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