The Pathology of Malignant Lymphoma in Cattle: A Study of 1113 Cases
1965
Smith, Hilton A.
About 1100 cases of malignant lymphoma were studied. Malignant lymphomas in cattle occur mostly at the older ages but they are by no means absent in the very young. Sex, breed and season of the year have little significance. Nearly all organs and tissues are susceptible to invasion, but some much more so than others, lymph nodes and heart being outstanding. Several histological types are described, as well as a relation to Hodgkin's disease. Reactions by eosinophils, plasma cells and other cells are described and an attempt made to evaluate them etiologically. Considerable evidence suggests that this neoplastic disease originates as an unsuccessful, generalized defensive reaction.
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