Beta-carotene increases lung cancer incidence in cigarette smokers
1996
De Luca, L.M. | Ross, S.A.
Clinical trials were designed to validate the protective effect of beta-carotene in populations of cigarette smokers at high risk for lung cancer development. Strikingly, an increase in lung cancer resulted following beta-carotene supplementation in two separate studies in Finland and the United States. These trials were conducted without any evidence that beta-carotene prevents lung cancer in animal models.
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