Bioaccumulation and elimination of endosulfan in zebra fish (Brachydanio rerio)
1992
Toledo, M.C.F. | Jonsson, C.M.
The bioaccumulation and elimination of endosulfan in zebra fish (Brachydanio rerio) were investigated in a semi-static bioassay. The pesticide mean concentration in water was 0.3 micrograms litre-1 and the level of endosulfan residues (alpha+beta-isomers+endosulfan sulfate) in the exposed fish at day 21 was 0.81 (+/- 0.12) micrograms g-1 body weight. The estimated value of the bioconcentration factor (BCF) was 2650 (+/- 441), the total endosulfan residues being eliminated with a biological half-life of four days. Histopathological studies showed predominantly lipid accumulation in the liver and necrotic focus in the gills of exposed fish.
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