Binding of Leishmania promastigotes to macrophages
1983
Zehavi, U. | El-On, J. | Pearlman, E. | Abrahams, J.C. | Greenblatt, C.L.
Leishmania tropica promastigotes, attachment to and engulfment by C3H peritoneal macrophages in vitro at 37 C, inhibition of attachment was affected by different sugars and by pre-treatment of promastigotes with galactose oxidase, oligosaccharides extending from promastigote and amastigote cell surfaces contain important proportion of non-reducing galactose as does L. tropica and L. donovani excreted factor, results suggest that Leishmania uses a cellular mechanism designed inter alia to remove damaged cells from blood circulation as a means of entering host cells
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