Long-term medical management of insulinoma in a rabbit
2022
Foxx, Jordan | Mans, Christoph | Strunk, Anneliese | Gasper, David
To describe the diagnosis and long-term medical management of insulinoma in a rabbit. A 9-year-old entire male mini lop rabbit was diagnosed with persistent mild hypoglycemia and had intermittent episodes of weakness and neurological deficits. Blood insulin levels were elevated, and a clinical diagnosis of insulinoma was made. Long-term treatment with oral prednisolone (final tapered dose: 0.15 mg/kg PO q48h) resulted in the resolution of clinical signs until the animal's death 17 months after the initial presentation. A single pancreatic nodule found on necropsy was histologically consistent with an islet cell tumor (insulinoma). Long-term management with a low dose of prednisolone was effective and safe in managing the clinical signs. Insulinoma should be a differential in rabbits presenting with neurological signs and are hypoglycemic.
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