Electrochemical Oxidative Cross-Coupling between Vinyl Azides and Thiophenols: Synthesis of gem-Bisarylthio Enamines
2021
Li, Guodong | Yu, Ke | Yang, Jiajun | Xu, Bo | Chen, Qianjin
An electrochemical radical strategy involving alkene substrates provides a powerful approach for alkene functionalization. Herein, we described the first electrochemical synthesis of gem-bisarylthio enamines from vinyl azides and thiophenols through the C–H/S–H cross-coupling. This electrochemical oxidative cross-coupling is characterized by good functional group tolerance, affording a series of gem-bisarylthio enamines in excellent yields, and was carried out at room temperature without additional oxidant, transition-metal catalyst, or base. Notably, the reaction could be easily performed on a gram scale with good efficiency.
Show more [+] Less [-]AGROVOC Keywords
Bibliographic information
This bibliographic record has been provided by National Agricultural Library