An allylated firefly luciferin analogue with luciferase specific response in living cells
2018
Ikeda, Yuma | Saitoh, Tsuyoshi | Niwa, Kazuki | Nakajima, Takahiro | Kitada, Nobuo | Maki, Shojiro A. | Sato, Moritoshi | Citterio, Daniel | Nishiyama, Shigeru | Suzuki, Kōji
An allylated firefly luciferin was successfully synthesized and its bioluminescence properties were evaluated. When applied to cellular imaging in combination with Eluc, which is one of the commercially available luciferases, this analogue displayed a luciferase-specific bioluminescence signal with prolonged emission (>100 min).
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